Sepicalm™ S is a lipo-aminoacid-based complex enriched minerals and vectorized essential amino acids for all-around protection against stress, a genuine feeling of well-being, and skin comfort. It calms inflammation by targeting the core of the cells and significantly increases the production of cutaneous b-endorphins, without inducing the production of TNF-α (an inflammatory cytokine).
Sepicalm™ S inhibits primary inflammatory response, limiting the expression of genes responsible for the production of pro-inflammatory substances. It also induces degradation enzymes of the extracellular matrix reducing MMP-3 up to 25% and preserving skin's natural elasticity, firmness, and moisture-binding ability.
Reducing IL-6 and IL-8 (inflammation mediators) secretion in stressed epidermis and dermis, Sepicalm™ S calms and comforts the skin, limiting abrasion-induced or actinic erythema, the intensity of stinging, and redness after UV exposure. In addition, it comforts reactive skin suffering irritation related to the reduced thickness, age, genetics, and environmental conditions.
Thanks to its amphiphilic structure, Sepicalm™ S has an excellent cutaneous affinity, water-dispersible, and is easy to be incorporated in skin care preparations. Slightly colored and odorless, it is suitable for all types of products, especially if they contain irritating ingredients or calming and soothing action needed.