Peptides

There are numerous examples in physiology of peptide regulatory elements that play integral roles in basic homeostatic mechanisms such as injury-repair responses and other stimulus-response actions. Among these are well-known neuropeptides (e.g., bradykinins, endorphins); metabolism and fat storage regulators (e.g., neuropeptide Y, leptin, insulin); tanning and skin pigmentation-related peptides (e.g., α-MSH, ACTH, Agouti), and peptides involved in wound healing (e.g., FGF).

This large group of innovative cosmeceutical ingredients triumphed in the world of skincare products during the last two decades. Peptides are chains of amino acids that are attached in a specific order. Amino acids are naturally occurring in the body and are vital to everyday living processes. Peptides can be made up of 2 or more amino acids that can stimulate different responses within the body. As a result, peptides serve as tiny messengers that can be sent to kick the skin into gear and make it look better.

Peptides are leading a beauty revolution due to their excellent multi-functional properties; formularies are scrambling to access the latest advances in cosmetic peptide technology. In addition, their "Botox-like" performance, activation of collagen and elastin production, and skin-lightening effect make them very efficient against coarse wrinkles and hyperpigmentation of the skin.

Idealift™
This lipopeptide exhibits good stimulating results on elastin production. As a result, Acetyl Dipeptide-1 Cetyl ester fights against cutaneous sagging and decreases the visible effects of gravity on the skin.
Acetyl Heptapeptide-9 mimics the TGFβ. Acetyl Heptapeptide-9 effects on fibroblasts, stimulating collagen, elastin, and other components of ECM production.
Acetyl octapeptide-3
Acetyl Octapeptide-3 is a brilliant, new, deep penetrating, powerful amino-peptide with a fantastic ‘BOTOX® like’ effect.
Acetyl Tetrapeptide-5
Acetyl Tetrapeptide-5 is a fantastic, super effective, naturally derived tetrapeptide that helps reduce the look of puffy eye bags and dark circles under the eyes and helps prevent them from reappearing.
GHK tripeptide

Aldenine® captures noxious RCS (reactive carbonyl species), which skin cells cannot detoxify by themselves when submitted to sunlight. Plant proteins contained in Aldenine® selectively boost the synthesis of Collagen III.

Decarboxy Carnosine
Alistin® (Decarboxy Carnosine) is a synthetic antiaging pseudodipeptide with high stability and resistance to enzymatic hydrolysis, that cell membranes oxidative stress and dermal fiber from cross-linking.
Argireline® Acetyl Hexapeptide-8
Acetyl Hexapeptide-8 is a mimic of the N-terminal end of SNAP-25. It competes with the natural protein for a position in the SNARE complex and relaxes facial muscles, destabilizing its formation without breaking any component.
Argirelox is a complex that combines the power of two revolutionary peptides fighting against expression lines and deep wrinkles by relaxing facial muscles.
Beta-White™ is an innovative biomimetic encapsulated (liposome) whitening peptide Oligopeptide-68 with a significant lightening effect. It reduces skin pigmentation and discolorations as well as age spots
Bio Placenta is a combination of five synthesized growth factors (EGF, IGF-1, acidic FGF, alkaline FGF, VEGF), amino acids and vitamins. Stimulates cell growth and skin tissue repair.
Biotinoyl Tripeptide-1
Thanks to stimulating peptide that promotes anti-aging processes in the follicle, encouraging anchoring of molecules, supporting hair growth, and slowing down premature hair loss.
Calmosensine™
Powered with triple-action lipopeptide Acetyl Dipeptide-1 Cetyl ester, Calmosensine™ leaves a significant anti-aging effect, boosting elastin production, mimic-muscle relaxation, and releasing precursor of endorphins (well-being hormones).
Red Clover
Capixyl is a bio-mimetic peptide with a red clover extract. It's an Hair Care Complex with anti-aging properties.
Caprooyl tetrapeptide-3
Caprooyl tetrapeptide-3 is a biomimetic lipopeptide structure based on TGF-ß (transforming growth factor beta) that plays an essential role in the natural production of the extracellular matrix components.
ChroNoline™
CroNoline™ is a specially formulated amino acid combination, which recreates growth factors found in youthful skin.
Formulated to regulate collagen fiber formation, Collagen Regulator Tetrapeptide binds to collagen fibrils to dramatically restore skin suppleness and enhance lift.
GHK-Cu

Numerous skincare products based on copper-peptide complexes are increasingly finding clinical and cosmeceutical uses. The biological basis for these actions is GHK (Tripeptide-1), a peptide generated during tissue damage with a very high affinity for copper (Cu2+).

Cyclotetrapeptide-24 Aminocyclohexane Carboxylate
RonaCare® Cyclopeptid-5 rapidly gives the skin a fresher and more youthful appearance. The peptide replicates the natural processes of skin communication and repair.
Dermaxyl before after
Ceramide 2 replenishes the lipid barrier and improves the skin's water-binding ability, smoothing fine lines and deep wrinkles. Palmitoyl Hexapeptide-12 stimulates fibroblasts' mobility and boosts elastin production, improving skin elasticity and firmness.
Tripeptide-9 Citrulline

Skin aging is a progressive accumulation of damage, beginning at the molecular level within the dermal cells. Transition metals are one of the factors responsible for the formation of highly reactive and DNA-damaging species (free radicals).

Eyeliss Before After
Eyeliss™ is a peptide complex consisting of three biologically active ingredients: Hesperidin methyl chalcone, Dipeptide-2 (Valyl-Tryptophane; Dipeptide-VW), a lipopeptide Palmitoyl Tetrapeptide-7 (Pal-GQPR) that prevents puffiness and diminishes under-eye bags.
Golden Collagenine combines gold and platinum with the efficacy of peptides to dramatically reduce wrinkles.
Haloxyl™ is a peptide complex based on four biologically active molecules, including matrikine lipopeptides Palmitoyl Tripeptide-1 (Pal-GHK) and Palmitoyl Tetrapeptide-7 (Pal-GQPR), iron chelating N-hydroxysuccinimide (NHS), and a flavonoid chrysin, that eliminates under-eye bags and dark circles.
Heptapeptide-15 mimics skin’s natural growth factors, stimulating fibroblasts differentiation and proliferation and enhancing extracellular matrix components production, such as collagen, elastin, and GAGs.
GHK tripeptide
Active ingredient with boosting and moisturizing long-lasting effect, enhanced by its anti-free radical activity, thus preserving the youthfulness of lips.
Leuphasyl® Pentapeptide-18
Pentapeptide-18 acts similar to natural enkephalins (proven in vitro study): it couples to the enkephalin receptor on the outside of the nerve cells, relaxing expression muscles and smoothing wrinkles.
N-Prolyl Palmitoyl Tripeptide-56 Acetate; Matrixyl® Morphomics™
N-Prolyl Palmitoyl Tripeptide-56 Acetate is a new, innovative, and award-winning peptide that boosts collagen and fibronectin production, improving extracellular matrix structure, fibers organization, and skin density.
Matrixyl™ Before After

Naturally occurring peptides in the skin perform critical roles in skin maintenance and repair, and there is growing interest in harnessing these effects for therapeutic and cosmetic use.

Matrixyl™ 3000 Sederma
Matrixyl 3000 combines two peptides that help to improve the cellular health of the skin cells, specifically the skin’s extracellular matrix.
Palmitoyl Tripeptide-38
Matrixyl™ synthe’6™ is a potent peptide that boosts six skin-rebuilding essentials: macromolecules - proteins and glycosaminoglycans.