Myristoyl tetrapeptide-6

Transforming growth factor (TGF-β), a member of a large family of secreted peptide growth factors is known to play a prominent role in the accumulation of ECM (extracellular matrix) components by increasing the expression of ECM genes, such as collagen, elastin, fibronectin, and proteoglycan. Myristoyl tetrapeptide-6, a mimic peptide of TGF-β, acts via the TGF-β signaling pathway and thereby up-regulates ECM proteins such as collagen and fibronectin.

In vitro and in vivo results show that Myristoyl tetrapeptide-6 significantly increases the expression of type I procollagen and fibronectin, efficiently reduces fine lines and wrinkles, and helps to maintain dermal thickness. Myristoyl tetrapeptide-6 can be incorporated in cosmetic formulations such as emulsions, oily sera, gels, and creams for anti-aging and anti-wrinkle purposes.

Functions
Anti-aging
Firming
Smoothing
Skin conditioning
Synonyms
DermaPep™ A420

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