Palmitoyl Tetrapeptide-72 Amide

Functions
Firming
Smoothing
Anti-aging
Skin conditioning
CAS Number(s)
2493255-49-3
FDA UNII
QV5FX82RZ2

Palmitoyl Tetrapeptide-72 Amide is a synthetic lipo-peptide with sequence Pal-His-Tyr-Arg-Ala-NH2 that boosts expression and production of Mohawk, a homeodomain protein abundantly expressed in the young skin and actively involved in the regeneration of EMC components and connective tissue in different parts of the body. It is known under the trade name Skinarch™.

Increasing Mohawk production, Palmitoyl Tetrapeptide-72 Amide consequently increases the expression and production of different types of collagen. In addition, it enhances gene expression responsible for synthesizing extracellular matrix (ECN) components and downregulates genes of enzymes that break down ECM structural proteins.

Besides boosting collagen synthesis, Palmitoyl Tetrapeptide-72 Amide enhances its density, organization, and fibril thickness. Applied topically, it exhibits wrinkle smoothing, rejuvenating, and anti-aging properties, proven with in vivo studies.

Synonyms
Skinarch™

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