sh-Polypeptide-93 is a synthetic recombinant human connective tissue growth factor (CTGF) analog peptide composed of 324 amino acids. It mimics an Insulin-like Growth Factor (IGF)-binding domain of CTGF regulating the expression of genes responsible for collagen production in fibroblasts.
CTGF expression levels are reduced in aged human skin, so the topical application of sh-Polypeptide-93 mimics the growth factor action boosting collagen production, improving skin elasticity, and increasing the thickness of the dermis.
sh-Polypeptide-93 is a safe, and effective ingredient for anti-aging skin care applications with skin firming, anti-wrinkle, and wound healing properties.
Functions
Anti-aging
Firming
Smoothing
Regeneration booster
Skin conditioning
Synonyms
Clairesome-CT
Insulin-Like Growth Factor-Binding Protein 8
Related ingredients
1,2-Hexanediol is glycol alcohol (with two hydroxy groups on 1 and 2 positions and six carbon atoms), a multifunctional ingredient used as a solvent, emollient, moisturizing agent, and preservative in skin and hair care applications.
Abyssinian oil (Crambe oil) achieves a significant improvement on the surface structure as well as the evenness of the skin tone.
This lipopeptide exhibits good stimulating results on elastin production. As a result, Acetyl Dipeptide-1 Cetyl ester fights against cutaneous sagging and decreases the visible effects of gravity on the skin.
Acetyl Heptapeptide-9 mimics the TGFβ. Acetyl Heptapeptide-9 effects on fibroblasts, stimulating collagen, elastin, and other components of ECM production.
Acetyl Octapeptide-3 is a brilliant, new, deep penetrating, powerful amino-peptide with a fantastic ‘BOTOX® like’ effect.
Acetyl Tetrapeptide-5 is a fantastic, super effective, naturally derived tetrapeptide that helps reduce the look of puffy eye bags and dark circles under the eyes and helps prevent them from reappearing.
Acmella Oleracea is an exotic plant, also known as Paracress. In the Indian Ocean region, it is called "Mafane". Reduces facial muscle micro-contractions, smoothes and reduces lines and wrinkles.
Acnacidol™ BG is a clinically tested complex that contains Queen bee acid (10-HDA or 10-Hydroxydecanoic Acid found in Royal Jelly that controls and reduces sebum and the appearance of acne.
Naturally existing in our bodies as part of the molecule adenosine triphosphate (ATP), responsible for transporting energy for numerous cellular and muscular functions in our body
Alanine is an amino acid permanently produced in the human body. It is included in beauty formulations as an effective skin humectant.
Alistin® (Decarboxy Carnosine) is a synthetic antiaging pseudodipeptide with high stability and resistance to enzymatic hydrolysis, that cell membranes oxidative stress and dermal fiber from cross-linking.