CAS Number(s)

Voluform™ (Palmitoyl Isoleucine) is a lipo-amino acid, an active ingredient that acts on every layer of the skin, providing volume, firming, and detoxifying dermal tissues. It leaves a volufirming effect on both young and old skin maintaining healthy adipocytes (fatty cells), stimulating cell functionality, and preventing their aging (deteriorated differentiation into MAD cells, non-functional adipocytes).

Thanks to the reinforced meshing of dermal fibroblasts, Palmitoyl Isoleucine exhibits a visible skin-firming effect, enhancing contractile forces of the fibroblasts by up to 94% and improving collagen organization. Increased dynamic interaction between the fibroblasts and the extracellular matrix (ECM) fibers provides more suitable cell adhesion and better anchoring, exposing a younger appearance, and firmer and supple skin.

Voluform™ increases the gene expression of collagen-1 by up to 8% and of its chaperone protein serpin-1H by up to 26%. In addition, it protects the Extracellular Matrix from degradation inhibiting an enzyme responsible for breaking down ECM components MMP-2 up to 77% and promoting its antagonist TIMP-2 by 55%.

Stimulating proteasome, a powerful cellular detoxifier, Palmitoyl Isoleucine revives specialized enzymatic systems turned sluggish by stress or aging, eliminating damaged proteins. Besides detoxification, it protects the cell's DNA and membranes from very reactive OH- hydroxyl radicals, exhibiting a potent antioxidant effect.

Active ingredients (or INCI)

Palmitoyl Isoleucine

What are the benefits of Voluform™ (Palmitoyl Isoleucine) for the skin?


Voluform™ is a preservative-free and Ecocert-certified ingredient with multiple benefits including:

  • Provides volume and elasticity effect for face or bust
  • Corrects wrinkles, sculpting the face from the inside out
  • Boosts epidermis renewal, exposing youthfulness and healthy radiance.