Palmitoyl Tetrapeptide-7

Functions
Anti-aging
Firming
Skin conditioning
CAS Number(s)
221227-05-0
FDA UNII
Q41S464P1R

Palmitoyl Tetrapeptide-7 (also known as Rigin™; former designation: Palmitoyl Tetrapeptide-3) is a lipopeptide from Sederma designed to mimic DHEA activity and restore cytokine balance to mature skin. The lipo-tetrapeptide with sequence Pal-GQPR, a fragment of immunoglobulin G, is sometimes referred to as the "youth hormone molecule."

DHEA (Dehydroepiandrosterone) decreases with aging, causing an increase in interleukin-6. Palmitoyl Tetrapeptide-7 helps skin look younger by correcting this imbalance and reducing the basal and UV-induced secretions of interleukin-6 in the keratinocytes and fibroblasts, just as DHEA does.

Ingredients

Palmitoyl Tetrapeptide-3
Synonyms
Rigin™
F.A.Q.

How Palmitoyl Tetrapeptide-7 keeps the skin younger?

Palmitoyl Tetrapeptide-7 reduces Interleukin-6 (IL-6) production by the critical cells keratinocytes and fibroblasts in the skin. Interleukin-6 is a mediator of inflammation that leads to more rapid degradation of the extracellular matrix components, promoting wrinkles formation and lessening firmness and elasticity of the skin.

Reduction of IL-6 and other pro-inflammatory agents, Palmitoyl Tetrapeptide-7, protects extracellular matrix components from degradation, preserving skin's natural youthfulness and boosting its replenishment.

Related ingredients

1,2-Hexanediol
1,2-Hexanediol
1,2-Hexanediol is glycol alcohol (with two hydroxy groups on 1 and 2 positions and six carbon atoms), a multifunctional ingredient used as a solvent, emollient, moisturizing agent, and preservative in skin and hair care applications.
Abyssinian Oil
Abyssinian Oil
Abyssinian oil (Crambe oil) achieves a significant improvement on the surface structure as well as the evenness of the skin tone.
Acetyl Dipeptide-1 Cetyl ester
Acetyl Dipeptide-1 Cetyl ester
This lipopeptide exhibits good stimulating results on elastin production. As a result, Acetyl Dipeptide-1 Cetyl ester fights against cutaneous sagging and decreases the visible effects of gravity on the skin.
Acetyl Heptapeptide-9
Acetyl Heptapeptide-9 mimics the TGFβ. Acetyl Heptapeptide-9 effects on fibroblasts, stimulating collagen, elastin, and other components of ECM production.
Acetyl Tetrapeptide-5
Acetyl Tetrapeptide-5
Acetyl Tetrapeptide-5 is a fantastic, super effective, naturally derived tetrapeptide that helps reduce the look of puffy eye bags and dark circles under the eyes and helps prevent them from reappearing.
Acmella Oleracea Extract
Acmella Oleracea Extract
Acmella Oleracea is an exotic plant, also known as Paracress. In the Indian Ocean region, it is called "Mafane". Reduces facial muscle micro-contractions, smoothes and reduces lines and wrinkles.
Acnacidol™ BG
Acnacidol™ BG
Acnacidol™ BG is a clinically tested complex that contains Queen bee acid (10-HDA or 10-Hydroxydecanoic Acid found in Royal Jelly that controls and reduces sebum and the appearance of acne.
Adenosine 5 Triphosphate (ATP)
Adenosine 5 Triphosphate (ATP)
Naturally existing in our bodies as part of the molecule adenosine triphosphate (ATP), responsible for transporting energy for numerous cellular and muscular functions in our body
Alanine
Alanine
Alanine is an amino acid permanently produced in the human body. It is included in beauty formulations as an effective skin humectant.
Algae Extract
Algae Extract
Contains micro-nutrients such as iron, manganese, zinc, magnesium, copper.
Alistin®
Alistin®
Alistin® (Decarboxy Carnosine) is a synthetic antiaging pseudodipeptide with high stability and resistance to enzymatic hydrolysis, that cell membranes oxidative stress and dermal fiber from cross-linking.
Alpha-Glucan Oligosaccharide
Alpha-Glucan Oligosaccharide
Thanks to the specificity of its inter-glycosidic bonds, Alpha-Glucan is a selective substrate for the nutrition and development of the skin's saprophytic (beneficial) flora to the detriment of undesirable opportunists flora (pathogenic or not) ready to invade the skin at the slightest sign of imbalance.