R-Clostridium Botulinum Polypeptide-1

Facial moisturizers, nutrient serums, and even daily cleansers claim to contain powerful ingredients that stave off the development of undesirable, yet seemingly inevitable, extrinsic signs of aging - from wrinkles to age spots to sagging skin. One tactic to combat the aging process is cosmetic surgery. Procedures such as face lifts, laser resurfacing, or liposuction can be costly and painful.

For the most part, the methods are available to a very small segment of elite consumers and are not without their faults and potential hazards. Since being approved by the FDA in April 2002 for cosmetic applications, there has been an increasing trend in the use of botulinum toxin for these purposes.

This protein toxin R-Clostridium Botulinum Polypeptide-1 derived from the fermentation of Clostridium botulinum bacteria, was historically used as a medical treatment for localized movement disorders such as blepharospasm (an involuntary movement of the eyelid) or cervical dystonia (characterized by involuntary contractions of the neck muscles).

It functions by temporarily paralyzing muscle fibers in order to relax the muscles affected. Frequently referred to as Botox®, R-Clostridium Botulinum Polypeptide-1 is now widely marketed for “the temporary improvement in the appearance of moderate to severe glabellar lines in adult men and women”. These ‘glabellar lines’ are more commonly called wrinkles.

The most common facial areas treated include crow’s feet, frown lines, laugh lines, and forehead wrinkles. The treatment requires that a small amount of R-Clostridium Botulinum Polypeptide-1 (botulinum toxin) is injected into the facial muscles that are responsible for creating wrinkles. The toxin inactivates these muscles, thereby diminishing the appearance of the facial lines dramatically.

However, the Botox® injection procedure is still costly, temporary (2-6 months), and not without risk. Hazards can include paralysis of nearby muscle tissue, facial pain and nausea, and in some cases, excruciating headaches. Perhaps worse, overuse of the treatment can result in permanent paralysis of treated muscles.

Functions
Smoothing
Skin conditioning
Synonyms
Botox®
BoNT/A
Botulinum toxin
Bototoxin