sh-Polypeptide-3 (former rh-Oligopeptide-5) is a single-chain synthetic recombinant peptide, an analog of human KGF (Keratinocyte Growth Factor). KGF was first described in 1989 as a human growth factor that stimulated epithelial cell proliferation.
sh-Polypeptide-3 affects the proliferation and differentiation of various cell types as it is a part of the Fibroblast growth factor (FGF) superfamily. KGF is involved in early hair growth as an important go-between.
sh-Polypeptide-3 promotes dermal cell adhesion, spreading, and proliferation and boosts regenerative processes in the skin and wound healing. It is an important mediator in epithelial repairs and mesenchymal interactions.
In addition, sh-Polypeptide-3 strengthens hair follicles, stimulating hair growth and enhancing their mechanical properties, health, and appearance. The former INCI name was rh-Polypeptide-3 (rh- prefix means recombinant human).Functions
Anti-aging
Regeneration booster
Smoothing
Hair growth stimulator
Skin conditioning
CAS Number(s)
148348-15-6
Synonyms
Recombinant Human Keratinocyte Growth Factor
CG-KGF
rh-Polypeptide-3
Human Oligopeptide-5
rh-Oligopeptide-5
Fibroblast Growth Factor 7
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