CAS Number(s)

A new peptide (tripeptide) formulation in order to reduce the most visible signs of skin aging. Syn®-Hycan has a dual effect. First, it boosts the skin's own production of hyaluronan, which binds skin moisture and protects and structures skin collagens and the skin cells of the dermis. Second, they replace the low hyaluronic acid level (e.g.) in mature skin, which loses its ability to bind water. By boosting the hyaluronan levels within the dermis, Syn®-Hycan firms skin from the inside.

In addition, Syn®-Hycan increases the levels of two essential proteins present in the human skin, which boost and strengthen collagen fibers. These active substances work together to prevent wrinkle formation and slackening of the skin, the most visible signs of skin aging.

By boosting the amount of hyaluronan in the dermis, SYN®-HYCAN firms the skin from the inside out. In contrast, when hyaluronan is applied topically, it can act only as a good humectant on the skin's surface. This incredible ingredient also increases decorin and lumican levels, which improve collagen fibers by making them thinner and stronger. Both SYN®-HYCAN modes of action work together to reduce wrinkle formation and skin sagging – the most visible signs of aging.

Scientific trials have provided convincing evidence of SYN®-HYCAN's efficacy in remodeling facial contours. When tested in normal human fibroblasts, this peptide was shown to increase skin-identical hyaluronic acid synthesis by a factor of 4, while also boosting the production of decorin (73%) and lumican (66%). A double-blind study was also performed with 40 female volunteers aged 55–65, demonstrating visible skin sagging. In addition to noticing improvements in the firmness of their skin, the participants reported that it felt softer and more hydrated. In fact, SYN HYCAN significantly increased tension by 3%, tonicity by 17%, and firmness by 7%.


Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate

Ingredient products

MBR® Medical Beauty Research
MBR® Medical Beauty Research
MBR® Medical Beauty Research