Effipulp®

A fruit native to Mexico, the Avocado was consumed more than 10,000 years ago by the Aztecs and Mayas and was imported to Europe in the 17th century. The varieties used to produce Effipulp® are mainly harvested in Latin America and Africa. Effipulp® is a peptide concentrate produced by enzymatic hydrolysis of defatted Avocado pulp (cake).

After freeze-drying, we obtain a stabilized powder on an organic maltodextrin carrier, free of preservatives. This green process respects the natural character of the fruit. This dry, water-soluble extract, has a unique composition of peptides with low molecular weight (‹10 kDa). Effipulp® is approved for the formulation of finished products certified by Ecocert.

Effipulp ® is capable of reducing the accumulation of senescence-induced oxidized proteins thanks to its action on the following:

• Thioredoxin (repair system): gene expression; +177% (in-vitro test, fibroblasts, 0.005% Avocado peptides; 48 hours).
• Proteasome activity (elimination system): +43% (in-vitro test, senescent fibroblasts, 0.005% Avocado peptides; 1h45).

In addition, Effipulp® stimulates the synthesis of Filaggrin and Transglutaminase (cornified envelope), two compounds essential for proper cohesion and resistance of the stratum corneum. In this way, Effipulp® preserves the moisture content of the skin.

Effipulp ® stimulates endogenous synthesis of key hygroscopic molecules of the epidermis and dermis, such as Hyaluronic Acid. An emulsion containing 0.6% Effipulp ® was applied on skin explants vs. a placebo (one application every 24 hours for 72 hours).