Biosaccharide gum-2

Our organism is controlled by a communication network that maintains physiological balance. This communication is a dynamic relationship maintained between a transmitter and a receiver through messages carried from a specific channel. The skin concentrates a large number of messages that are exchanged between cells through mediators. Due to aging, skin cell communication is compromised.

Keratinocytes are involved in the first line of defense of the cutaneous immune system, they synthesize several pro-inflammatory mediators, such as cytokines that are released after activation by different stimuli. The primary cytokines IL-1α, IL-1-β, and TNF-α stimulate mechanisms capable of triggering a skin inflammatory response, through interaction with specific keratinocyte receptors. In addition to modulating the inflammatory process, they are also involved in cell proliferation and differentiation.

Biosaccharide gum-2 is a polysaccharide obtained by biotechnology, through bacterial fermentation of plant substrates that forms a branched structure and a sequence of sugars, rich in rhamnose. It acts as a trap, attaching itself to the membrane receptors of attacked keratinocytes, modulating the chain reaction of inflammation.

Consequently, Biosaccharide gum-2 prevents accelerated aging caused not only by a particular agent but also by UV radiation, pollution, and exposure to chemicals, among others. Another important action is the stimulation of the release of β-endorphins, known as pleasure molecules, thus combining protection with well-being.

In short, Biosaccharide gum-2 is a desensitizing agent with a specific fixation ability on keratinocyte receptors. It slows down the aging process and stimulates the synthesis of β-endorphins. Inhibiting the activity of PLA2 (Phospholipase A2) and decreasing the release of PGE2 (Prostaglandin E2), Biosaccharide gum-2 reduces the skin inflammatory process including UV- and retinoid-induced irritation. It is a recommended ingredient for oily skin and baby care products.

Functions
Anti-inflammatory
Soothing
Desensitizing agent
Anti-aging
Skin conditioning
CAS Number(s)
283602-75-5
758716-52-8
Synonyms
Rhamnosoft® HP