Methyl Undecylenoyl Dipeptide-16

Functions
Skin whitening agent
Anti-inflammatory
Skin conditioning

Alpha-MSH a melanocyte-stimulating hormone, is one of the factors in the regulation of melanin production. It is involved in the control of tyrosinase activity, melanin synthesis, and melanosome transfer.

Methyl Undecylenoyl Dipeptide-16, a derivative of Methyl undecenoyl leucinate, interacts with MC1R, a receptor for alpha-MSH, and competes against its natural ligand alpha-MSH. It prevents any further activation of melanogenic genes such as tyrosinase, TRP1, TRP2 (DCT), MITF, and POMC and finally blocks melanin production.

Furthermore, Methyl Undecylenoyl Dipeptide-16 reduces UVB-induced inflammation and thereby provides a significant photoprotective effect.

In vitro and in vivo study results show that Methyl Undecylenoyl Dipeptide-16 is far more effective than whitening ingredients such as arbutin. In vivo clinical study proved that it is a very effective and safer agent to make the skin brighter, youthful, and radiant.

Dermatological tolerance standard testing has been performed on Methyl Undecylenoyl Dipeptide-16 which has shown neither cytotoxic effects nor any irritation or sensitization reaction in healthy volunteers with an occlusive single patch test.

Synonyms
DermaPep™ W220

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