Although hair disorders are not life-threatening, their profound impact on social interaction and on patients’ psychological aspects is undeniable. The demand for hair loss treatment has led to a multibillion-dollar industry. Despite this, most currently marketed products are ineffective, evidenced by the fact that the FDA has approved only two treatments for hair loss, one of which is a minoxidil solution.
Dipeptide-13 is a small molecule peptide containing tryptophan and glutamic amino acids (L-Glu-L-Trp) initially found in the calf thymus peptide complex. It has immunomodulatory, anti-stress, and anti-tumor action and showed good results in the treatment of atopic dermatitis.
Myristoyl Dipeptide-13 is a lipo-derivative of Dipeptide-13 (Myristoyl-Glu-Trp) that was developed as an effective hair growth stimulator and anti-hair loss agent.
Other in vivo study results show that Myristoyl Dipeptide-13 inhibits hair loss, strengthens hairs, and promotes hair regrowth eventually. It promotes cell proliferation in human dermal papilla cells, fibroblasts, and keratinocytes. It also stimulates melanin synthesis in melanocytes.