Myristoyl Dipeptide-13

Although hair disorders are not life-threatening, their profound impact on social interaction and on patients’ psychological aspects is undeniable. The demand for hair loss treatment has led to a multibillion-dollar industry. Despite this, most currently marketed products are ineffective, evidenced by the fact that the FDA has approved only two treatments for hair loss, one of which is a minoxidil solution.

Dipeptide-13 is a small molecule peptide containing tryptophan and glutamic amino acids (L-Glu-L-Trp) initially found in the calf thymus peptide complex. It has immunomodulatory, anti-stress, and anti-tumor action and showed good results in the treatment of atopic dermatitis.

Myristoyl Dipeptide-13 is a lipo-derivative of Dipeptide-13 (Myristoyl-Glu-Trp) that was developed as an effective hair growth stimulator and anti-hair loss agent.
 

In vitro study results showed that Myristoyl Dipeptide-13 prolongs the anagen phase and delays the entry toward the catagen phase by promoting the proliferation of dermal papilla cells, fibroblasts, and keratinocytes and increasing melanin production.

Other in vivo study results show that Myristoyl Dipeptide-13 inhibits hair loss, strengthens hairs, and promotes hair regrowth eventually. It promotes cell proliferation in human dermal papilla cells, fibroblasts, and keratinocytes. It also stimulates melanin synthesis in melanocytes.

Functions
Hair growth stimulator
Anti-hair-loss
Skin conditioning
Synonyms
DermaPep™ Pepanagen