rh-Polypeptide-13, also known under the trade name CG-Noggin (former designation Human Oligopeptide-18; rh-Oligopeptide-18), is a synthetic single-chain recombinant polypeptide that promotes hair growth while inhibiting its depigmentation. It was specially developed to strengthen and stimulate hair follicles.
In addition, rh-Polypeptide-13 enhances blood circulation in the scalp, revitalizing hair follicles. CG-Noggin is an antagonist of BMP4 (Bone Morphogenetic Protein 4) that inhibits hair follicle development.
So, CG-Noggin stimulates hair placode formation. Additionally, it significantly enhances epidermal thickness and cell proliferation. Scientific studies have shown that CG-Noggin stimulates hair follicle development in embryonic skin organ culture.
It is a safe and effective ingredient against hair loss and depigmentation (white hair). CG-Noggin is used in high-end hair, lash, and eyebrow care products.