sh-Pentapeptide-6 Trifluoroacetate

Functions
Firming
Smoothing
Anti-aging

sh-Pentapeptide-6 Trifluoroacetate synthetic recombinant peptide that boosts stratifin protein production improving bio-messaging between skin layers (epidermal-dermal "cross-talk") and leading to dermal remodeling and wrinkle repair.

Wrinkle repair technology is linked with stratifin molecule, an epidermal bio-messenger that communicates with the dermis for matrix remodeling. sh-Pentapeptide-6 Trifluoroacetate known under trade name Neomatrix™ is a pentapeptide inspired by wound healing science linked to skin communication and matrix remodeling.

In the skin, healing is the normal biological process for repairing injured tissues and is achieved through a dermal remodeling. step. sh-Pentapeptide-6 Trifluoroacetate is the first technology inspired simultaneously by:

  • Similarities between the wound healing process and wrinkle repair.
  • The importance of keratinocyte-fibroblast cross-talk in dermal remodeling.
  • The stratifin messaging role in epidermal-dermal communication and tissue remodeling.

Dermis remodeling is characterized by a fine balance between the synthesis of new extracellular matrix (ECM) coupled with the degradation of aged ECM (extracellular matrix) to avoid the accumulation of defective matrix proteins. sh-sh-Pentapeptide-6 Trifluoroacetate goes beyond the traditional approach, which is merely to boost the synthesis of proteins in the dermis without considering that skin can accumulate aged and/or defective proteins leading to less functional cells.

sh-Pentapeptide-6 Trifluoroacetate enhances epidermal stratifin expression to help skin optimize epidermal-dermal messaging profed in vitro, ex vivo. It improves ECM turnover balance through skin’s physiological MMPs expression for aged collagen degradation in parallel with neo-collagen synthesis profed in vitro.

In addition, Neomatrix™ promotes new matrix production including: Pro-collagen, Collagen I, Collagen III, Hyaluronic acid (in vitro, ex vivo). It maintains dermal reorganization helping skin to improve fibroblast strength and optimize matrix contraction (in vitro).

Synonyms
Neomatrix™

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