sh-Polypeptide-12 is a synthetic recombinant single-chain peptide, an analog of human Interleukin 4 (IL-4) that plays the role of an anti-histamine or immune-suppressor agent to reduce scratching by inhibiting the autoimmune response. It is known under the trade name CG-IL-4; the former INCI name was Human Oligopeptide-15 or rh-Oligopeptide-15.
sh-Polypeptide-12 lessens skin irritation on the lower part of the legs, generally related to circulatory problems. It is effective against psoriasis, an abnormal immune system that produces too many of the immune cells. IL-4 treatment decreases PASI (Psoriasis area and severity index).
Functions
Soothing
Anti-psoriasis
Skin conditioning
Synonyms
rh-Polypeptide-12
CG-IL-4
Human Oligopeptide-15
rh-Oligopeptide-15
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