sh-Polypeptide-9 is a synthetic recombinant analog of human VEGF (Vascular Endothelial Growth Factor). It enhances the division and migration of cytokine by increasing the permeation of serum protein in the capillary vessels.
sh-Polypeptide-9 boosts the production of protein a resolution enzyme causing cell restructuring. It increases the formation of skin with acceleration moving blood vessel cells and the development and division of new cells. It increases the permeability of the vascular wall and relieves vascular spasms. In addition, it activates the migration of monocytes in the layers of the skin.
VEGF enables newly formed blood vessels' survival while restraining cell death and derives growth and division of cells as taking charge of immunity control with constraints concerning antigen of a nerve cell. Restoring normal microcirculation of the scalp, sh-Polypeptide-9 is used in products for the treatment of alopecia. It has an anti-edematous effect, stimulating the renewal of skin microvessels and the development of a network of lymphatic vessels.
sh-Polypeptide-9 is diffusible and specific for endothelial cells suggesting that this molecule may play a unique role in the regulation of angiogenesis. VEGF plays a crucial role in the control of perifollicular vascularization during the hair cycle. It is used in high-end skin and hair care applications and famous complexes like Bio Placenta where it enhances the effect of fibroblast growth factors, promoting renewal and orderly restructuring of skin structures.