Activys® Anti-Glycation

Activys® Anti-Glycation is a complex ingredient that reduces the effects of glycation on the skin and minimizes the visible possible impact (redness) on sensitive skin. The capsule incorporates a ferment (Aspergillus). It is a potent antioxidant (increases the antioxidant levels in the skin by up to 12% (Antioxidant Score), rejuvenates the skin in 18 years (relative to the levels of glycation at D0 vs D28), and reduces the yellowish color of the skin (characteristic of skins with high levels of glycation-diabetics) in 1.5% Efficacy in 20 volunteers after 28 days of application.

Glycation and oxidation are two of the most important processes involved in skin aging. Glycation consists of a slow reaction of sugars such as glucose and ribose with amino acid groups of a protein. In dermatological terms, glycation is a spontaneous reaction of blood glucose with the dermal fibers of collagen and elastin.

The resulting glycation products accumulate inside and outside the cells and bind proteins of the plasma membrane, circulating proteins, and structural proteins, the latter of which most influence the skin's aging process.

The products resulting from glycation are known collectively as advanced glycation end products (AGE) by their English nomenclature (Advance Glycation End Products) and accumulate in the skin's extracellular matrix. In short, a chain reaction leads to stiffness and fragility, making the skin more sensitive.