Copper Tripeptide-1

Functions
Firming
Smoothing
Hydrating
Anti-aging
Skin conditioning
FDA UNII
6BJQ43T1I9
INCI name
Copper Tripeptide-1

Numerous skincare products based on copper-peptide complexes are increasingly finding clinical and cosmeceutical uses. The biological basis for these actions is GHK (Tripeptide-1), a peptide generated during tissue damage with a very high affinity for copper (Cu2+).

GHK-Cu is also a regular constituent in human plasma, existing at approximately 200 ng/ml at age 20 and dropping to 80 ng/ml at age 60. At hormonal levels, Copper Tripeptide-1 acts as a chemoattractant for fibroblasts (repairing cells) and activates a plethora of regenerative processes in the skin, such as angiogenesis, production of extracellular matrix components, including collagen, elastin, proteoglycans, glycosaminoglycans, etc, additionally activating metalloproteinases (MMPs) involved in tissue remodeling.

Copper-peptide complexes are used to stimulate the repair of damaged skin and bone, heal ulcerated stomach and intestinal lining (e.g., inflammatory bowel disease), improve the take of hair transplants, and stimulate hair growth.

In aged human skin, copper-peptide creams thicken skin, improve elasticity, and increase the density of the subcutaneous fat layer. GHK-Cu blocks ferritin channels and the release of tissue-damaging free (oxidative) iron after injury, thus blocking iron-catalyzed lipid peroxidation that often occurs after injury and interleukin-1 damage to pancreatic islet cells. The three-dimensional structure of GHK-Cu is strikingly similar to many pharmaceutical anti-ulcer (stomach) medicines. Two potential uses for a copper peptide that deserve more study are the reduction of scars and skin lesions and the systemic activation of wound healing before surgical procedures.
Synonyms
Prezatide Copper

Related ingredients

Biotinoyl Tripeptide-1
Biotinoyl Tripeptide-1
Thanks to stimulating peptide that promotes anti-aging processes in the follicle, encouraging anchoring of molecules, supporting hair growth, and slowing down premature hair loss.
Haloxyl™
Haloxyl™ is a peptide complex based on four biologically active molecules, including matrikine lipopeptides Palmitoyl Tripeptide-1 (Pal-GHK) and Palmitoyl Tetrapeptide-7 (Pal-GQPR), iron chelating N-hydroxysuccinimide (NHS), and a flavonoid chrysin, that eliminates under-eye bags and dark circles.
Liporeductyl®
Liporeductyl®
Liporeductyl® is a complex ingredient packed in a liposome, consisting of plant extracts, biologically active substances, and a peptide with four specific anticellulite actions.
Matrixyl™ 3000
Matrixyl™ 3000
Matrixyl 3000 combines two peptides that help to improve the cellular health of the skin cells, specifically the skin’s extracellular matrix.
Maxi-Lip Sederma
Maxi-Lip Sederma
A peptide-based wax, activates the protein and proteoglycan synthesis, which increases the density of the connective tissue and tangibly firms the lip‘s contours, moisturizes, restructures.
Palmitoyl Tripeptide-1
Palmitoyl Tripeptide-1
Palmitoyl Tripeptide-1 stimulates fibroblasts and enhances the production of collagen and GAGs, smoothing fine lines and deep wrinkles and improving the water-binding ability and elasticity of the skin.
Regestril™
Regestril™
Several studies in the 90s showed that on the cellular level stretch marks formation process starts with endogenous glucocorticoid (corticosteroids) secretion under influence of stress or hormonal changes during puberty or pregnancy.
Tripeptide-1
Tripeptide-1
An RCS scavenger helps prevent visible signs of premature aging from pollution and photo-aging. Tripeptide-1 is also a signaling peptide that stimulates the synthesis of extracellular matrix components, primarily collagen, hyaluronic acid, and other GAGs.
Trylagen ™
Trylagen ™
A ferment extract with two peptides (tripeptide-10 citrulline, tripeptide-1) and two proteins (wheat germ protein, soy protein) that boosts collagen synthesis. Trylagen boosts the synthesis of collagen types I, III, and IV, in order to increase collagen levels which are reduced or lost in the aging process.
Aldenine®
Aldenine®
Aldenine® captures noxious RCS (reactive carbonyl species), which skin cells cannot detoxify by themselves when submitted to sunlight. Plant proteins contained in Aldenine® selectively boost the synthesis of Collagen III.
Hilurlip™
Hilurlip™
Active ingredient with boosting and moisturizing long-lasting effect, enhanced by its anti-free radical activity, thus preserving the youthfulness of lips.
Copper Tripeptide-1 Palmitamide
Copper Tripeptide-1 Palmitamide
Copper Tripeptide-1 Palmitamide is a complex of copper with a synthetic lipopeptide, a modification of the famous GHK peptide (Tripeptide-1) in which terminal lysin's amino group is acylated with palmitic acid.