Elaself

As the skin is stressed during the aging process, the synthetic activity of cells decreases in general. The production of MFAP-4 is reduced and the whole process of elastin fiber formation is negatively involved from its first stage. Final elastic fiber is unable to mechanically support the skin structure which results in a decrease of important mechanical parameters of the skin in general.

Elaself contains a synthetic analog of human pentapeptide (sh-Pentapeptide-3) that mimics the fragments of MFAP-4 protein one of the key regulators of collagen production. It has a positive effect on the synthesis of MFAP-4 protein produced by fibroblasts and also the production of collagen. In addition, MFAP-4 protein is essential for the formation of elastic fibers by associating them together. This leads to an improvement in skin elasticity by 30% and a reduction of the appearance of fine lines and wrinkles, which is essential for maintaining youthful-looking skin.

Skin structural fibers organization

The structural conformation of elastic fibers is the key condition for its correct function in the skin. As skin ages, the synthetic activity of cells decreases in general. That’s the problem also in the case of MFAP-4 protein, which is responsible for the correct organization of elastic fibers. This MFAP-4 protein is a basic functional unit of connections between microfibrils that represent a scaffold for the amorphous elastin deposition during elastic fiber formation.

Elaself is a pentapeptide designed to mimic degrading fragments of the protein MFAP-4, which influences the expression of its gene on the basis of negative feedback. Consequently, this mechanism stimulates the production of this key protein, which supports the correct organization of elastic fibers.

Ingredients

Phenoxyethanol
Phosphate Buffered Saline
sh-Pentapeptide-3
Functions
Firming
Smoothing
Anti-aging

Related ingredients

Acetyl Dipeptide-1 Cetyl ester
Acetyl Dipeptide-1 Cetyl ester
This lipopeptide exhibits good stimulating results on elastin production. As a result, Acetyl Dipeptide-1 Cetyl ester fights against cutaneous sagging and decreases the visible effects of gravity on the skin.
Acetyl Heptapeptide-9
Acetyl Heptapeptide-9 mimics the TGFβ. Acetyl Heptapeptide-9 effects on fibroblasts, stimulating collagen, elastin, and other components of ECM production.
Acetyl octapeptide-3
Acetyl octapeptide-3
Acetyl Octapeptide-3 is a brilliant, new, deep penetrating, powerful amino-peptide with a fantastic ‘BOTOX® like’ effect.
Acetyl Tetrapeptide-5
Acetyl Tetrapeptide-5
Acetyl Tetrapeptide-5 is a fantastic, super effective, naturally derived tetrapeptide that helps reduce the look of puffy eye bags and dark circles under the eyes and helps prevent them from reappearing.
Acmella Oleracea Extract
Acmella Oleracea Extract
Acmella Oleracea is an exotic plant, also known as Paracress. In the Indian Ocean region, it is called "Mafane". Reduces facial muscle micro-contractions, smoothes and reduces lines and wrinkles.
Acnacidol™ BG
Acnacidol™ BG
Acnacidol™ BG is a clinically tested complex that contains Queen bee acid (10-HDA or 10-Hydroxydecanoic Acid found in Royal Jelly that controls and reduces sebum and the appearance of acne.
Adenosine 5 Triphosphate (ATP)
Adenosine 5 Triphosphate (ATP)
Naturally existing in our bodies as part of the molecule adenosine triphosphate (ATP), responsible for transporting energy for numerous cellular and muscular functions in our body
Alistin®
Alistin®
Alistin® (Decarboxy Carnosine) is a synthetic antiaging pseudodipeptide with high stability and resistance to enzymatic hydrolysis, that cell membranes oxidative stress and dermal fiber from cross-linking.
Alpha-Glucan Oligosaccharide
Alpha-Glucan Oligosaccharide
Thanks to the specificity of its inter-glycosidic bonds, Alpha-Glucan is a selective substrate for the nutrition and development of the skin's saprophytic (beneficial) flora to the detriment of undesirable opportunists flora (pathogenic or not) ready to invade the skin at the slightest sign of imbalance.
AquaCacteen™
AquaCacteen™
AquaCacteen™ is a botanical complex based on the Barbary fig stem extract and designed to soothe and calm irritated skin, protect from environmental stress factors, and deeply hydrate with long-lasting effects.
Argireline®
Argireline®
Acetyl Hexapeptide-8 is a mimic of the N-terminal end of SNAP-25. It competes with the natural protein for a position in the SNARE complex and relaxes facial muscles, destabilizing its formation without breaking any component.
Ascorbyl Tetraisopalmitate
Ascorbyl Tetraisopalmitate
Like other forms of Vitamin C, Ascorbyl Tetraisopalmitate helps prevent cellular aging by inhibiting the cross-linking of collagen, oxidation of proteins, and lipid peroxidation.