Coenzyme Q10 is present in dermal cells, where it stimulates ATP (cellular energy molecules) production and protects from oxidative damage (free radicals). Production of this enzyme cofactor depends on the Trans-prenyltransferase enzyme (also called Polyprenyl transferase or Transprenyl transferase) responsible for the reaction between quinone nucleus with farnesyl pyrophosphate.
Pentapeptide-34 Trifluoroacetate (known under the trade name Peptide Q10™) is a synthetic peptide with sequence Ala-Val-Leu-Ala-Gly-TFA that promotes the synthesis and activity of the Trans-prenyltransferase enzyme and boosts coenzyme Q10 production. As a result, it promotes intracellular ATP production and significantly improves cell protection against oxidative damage.
Energizing dermal cells, Pentapeptide-34 Trifluoroacetate boosts cellular functions, improving renewal rate, activity, and vitality. In addition, it enhances cells' natural protective mechanisms, fighting against free radicals, oxidative stress, and premature aging.
Ex vivo studies with dermal cell cultures treated with Pentapeptide-34 Trifluoroacetate showed that it protects cells from UVB- and peroxide-induced oxidative damage and effectively fights against glycation. In addition, it activates the synthesis of intracellular ATP and raises its levels in cutaneous cells.Incorporated in anti-aging formulations, Pentapeptide-34 Trifluoroacetate is a perfect compensational treatment of age-related Coenzyme Q10 decline, a remedy against physicochemical or environmental damaging factors, and a weapon against premature aging.
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