TIMP Peptide is an aqueous solution of matrix metalloproteases inhibiting lipo-peptide designed to decelerate photoaging.
Matrix Metaloproteases (MMPs) are cell surface enzymes with the capability of degrading extracellular proteins. MMPs can degrade collagen, elastin, and other components of the Extra Cellular Matrix (ECM).
MMPs can break down every ECM structural molecule, peri-cellular, and surface cellular proteins. These mechanisms include the alteration of cell-cell and cell-matrix interactions, release, activation, or inactivation of paracrine/autocrine molecules, which signal and lead to the potential of activation/inactivation of surface cell receptors, which can induce and accelerate premature photoaging.
Chronologic aging mechanisms, or those induced by UV exposure, induce the production of MMPs that eventually affect the skin.TIMP Peptide effectively fights against photoaging. This potent peptide shows inhibitory properties on the metalloproteases of the matrix. Its structure is based on the sequence of the breaking point of the collagen substrate. It simply chelates the active site of the Zn2+ ion and inactivates the MMP, a revolutionary approach to inhibiting and preventing photoaging.