Ascorbyl Tocopheryl Maleate

Functions
Antioxidant
Skin whitening agent
Emollient
Skin conditioning
CAS Number(s)
320616-16-8
488109-64-4
FDA UNII
D2G6259XR5

Ascorbyl Tocopheryl Maleate is a diester of Maleic acid with Vitamin C and E (l-Ascorbic acid and α-Tocopherol) used in personal care applications and the pharmaceutical industry, with properties intrinsic to both vitamins. It is sometimes called CME (vitamin C - Maleic acid - vitamin E; like its molecule).

Anhydrous Ascorbyl Tocopheryl Maleate is a white powder that is slightly soluble in water and stable in formula. It quickly hydrolyzes in the presence of strong bases (alkali conditions).

Incorporated in skin care applications, Ascorbyl Tocopheryl Maleate is an extraordinary antioxidant that scavenges reactive species, protecting dermal cells from oxidative damage and programmed death. It is also used as a skin conditioning agent and emollient. 

Manufacturers claim an excellent skin whitening effect, as it is a Vitamin C derivative and can inhibit tyrosinase activity, suppressing melanin production. There is no scientific data about the collagen-boosting effect intrinsic to ascorbic acid derivatives, but it is included in many anti-aging products.
Synonyms
2-L-ascorbyl 6-dalphatocopheryl 2-butenedioate
CME

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