Ceramide II (NG)

Functions
Hydrating
Barrier enhancer
Anti-aging
Skin conditioning
CAS Number(s)
2304-80-5
FDA UNII
C04977SRJ5

The ceramides are a class of complex lipids discovered in the superior strata of the epidermis. Considered the "key molecule" of the epidermis, ceramides constitute 40-50% of the lipids in the stratum corneum and are primarily involved in maintaining the water level within the epidermal layers. Therefore, considerable research has been devoted to obtaining them (extraction, synthesis) and their cosmetic use. In-vivo studies have shown that damaged skin treated with Ceramide 2 has a significantly increased ability to retain moisture and reduce Transepidermal Water Loss (TEWL) - indicating a restructuring of the lipid layers within the epidermis and a reestablishment of the integrity of the cutaneous barrier.

Ceramides strengthen the cutaneous barrier and regulate the water flux across the stratum corneum.

Ceramide II (NG), also known as N-stearoylsphinganine or Ceramide 2, is similar to dermal cells' membrane molecules and is a replica of the natural type 2 ceramide that protects and repairs the cutaneous barrier of the skin. In addition, it renews the skin's lipid layer, reduces transdermal moisture loss, and improves water-binding ability. As a result, the tropical application of  Ceramide 2 enhances the state and appearance of human skin, preventing and reducing the visible signs of aging.

It promotes natural, moisture-rich skin that is more likely to resist the early onset of aging. In addition, in high-end formulas, Ceramide NG may be combined with peptides (e.g., Palmitoyl Hexapeptide-12), which enhances the effectiveness of the entire formulation, delivering better results with lower concentrations.
Synonyms
Ceramide 2

Related ingredients

1,2-Hexanediol
1,2-Hexanediol
1,2-Hexanediol is glycol alcohol (with two hydroxy groups on 1 and 2 positions and six carbon atoms), a multifunctional ingredient used as a solvent, emollient, moisturizing agent, and preservative in skin and hair care applications.
Abyssinian Oil
Abyssinian Oil
Abyssinian oil (Crambe oil) achieves a significant improvement on the surface structure as well as the evenness of the skin tone.
Acetyl Dipeptide-1 Cetyl ester
Acetyl Dipeptide-1 Cetyl ester
This lipopeptide exhibits good stimulating results on elastin production. As a result, Acetyl Dipeptide-1 Cetyl ester fights against cutaneous sagging and decreases the visible effects of gravity on the skin.
Acetyl Heptapeptide-9
Acetyl Heptapeptide-9 mimics the TGFβ. Acetyl Heptapeptide-9 effects on fibroblasts, stimulating collagen, elastin, and other components of ECM production.
Adenosine 5 Triphosphate (ATP)
Adenosine 5 Triphosphate (ATP)
Naturally existing in our bodies as part of the molecule adenosine triphosphate (ATP), responsible for transporting energy for numerous cellular and muscular functions in our body
Alanine
Alanine
Alanine is an amino acid permanently produced in the human body. It is included in beauty formulations as an effective skin humectant.
Algae Extract
Algae Extract
Contains micro-nutrients such as iron, manganese, zinc, magnesium, copper.
Alistin®
Alistin®
Alistin® (Decarboxy Carnosine) is a synthetic antiaging pseudodipeptide with high stability and resistance to enzymatic hydrolysis, that cell membranes oxidative stress and dermal fiber from cross-linking.
Alpha-Glucan Oligosaccharide
Alpha-Glucan Oligosaccharide
Thanks to the specificity of its inter-glycosidic bonds, Alpha-Glucan is a selective substrate for the nutrition and development of the skin's saprophytic (beneficial) flora to the detriment of undesirable opportunists flora (pathogenic or not) ready to invade the skin at the slightest sign of imbalance.
Alpha-isomethyl Ionone
Alpha-isomethyl Ionone
Alpha-isomethylionone is a colorless to pale oily liquid, an isomer of Methyl Ionone, but its sweet orris-like scent is felt more attractive.
Ammonium Lactate
Ammonium Lactate
This food-grade ingredient is valued for its humectant and skin conditioning effects and is used as an anionic surfactant.
Apple extract
Apple extract
The Apple awakens energies and is said to have an exceptionally activating effect on the body. The scent contributes to an extremely refreshing and stimulating sensation.