Palmitoyl Sh-Tripeptide-5 Norisoleucyl Sh-Nonapeptide-1 is a lipo-peptide that acts as an antagonist of an α-MSH (α-Melanocyte-stimulating hormone). SH prefix means "synthetic human," so it is a synthetic peptide whose sequence is close to the melanotropin alpha hormone (α-MSH) that stimulates melanin production. Palmitoyl Sh-Tripeptide-5 Norisoleucyl Sh-Nonapeptide-1 binds to MC1R receptors on the melanocyte's surface, blocking the hormonal signal to increase melanin production. So, it acts as a skin-whitening agent that evens the skin tone, exposing a brighter, rejuvenated, and radiant complexion.
Thanks to its selective affinity with skin melanocytes, Palmitoyl Sh-Tripeptide-5 Norisoleucyl Sh-Nonapeptide-1 is used in advanced peptide complexes such as X50® Pure White and X50® Lightening as a targeting peptide that helps deliver the complex directly to melanocytes, boosting the effectiveness of the ingredient in minimal concentrations. Attached to the polymer capsule, it binds to the MC1R receptor, which breaks down the capsule, releasing active ingredients close to melanocytes.