X50 Lightening

X50 Lightening is a liposomal vitamin-peptide complex that intelligently lightens and brightens the skin. It is a skin-whitening agent that inhibits tyrosinase's enzymatic activity, helping lessen dermal pigmentation and even the skin tone. The liposomes contain 15% arbutin and 15% sodium ascorbyl phosphate (a vitamin C derivative).

X50 Lightening combines the ITD technology, which binds a peptide (a-MSH antagonist) to the outer layer of the Capsule X50®. This peptide shows an extraordinary affinity for the receptor MC1 at the melanocytes, therefore there is a selective interaction/bond with the target cell, initiating the internalization of the capsule in the melanocyte by endocytosis and delivering the encapsulated active ingredient into the cytosol of the melanocyte.

In this case, the external peptide acts as a peptidic ligand, directing the capsules to the cell receptor. It also acts as (active function) an antagonist of α-MSH. This peptide is conjugated to the outer layer of the capsule at 5% concentration.

Vitamin C, presented in the X50 Lightening as the derivative sodium ascorbyl phosphate (SAP), has been widely used as a skincare ingredient. It protects the skin, promotes cell turnover, and improves the skin's appearance. Additionally, it is an excellent anti-oxidant and offers skin balance properties to help correct uneven skin tone. SAP is degraded enzymatically in the skin to deliver vitamin C. It acts over the melanin production process to avoid hyperpigmentation and senile keratosis.