PerfectionPeptide P3

CAS Number(s)

PerfectionPeptide P3 is a biomimetic peptide-based complex for peeling to create perfect skin.

The skin's own permanent exfoliation renders the skin smooth and soft.
Desquamation is the natural exfoliation process of our skin. New keratinocytes are constantly formed in the basal layer of the epidermis. From there cells migrate and differentiate to form the outermost layer of the epidermis, the stratum corneum. At the surface, dead cells are continuously shedding – the skin remains smooth, soft, and evenly toned.

In aged skin natural exfoliation process slows down
As skin ages keratinocytes stick together stronger and the desquamation process becomes slow and irregular. The skin gets dry, rough, patchy, and scaly, and more and more uneven and its color turns dull and greyish.

PerfectionPeptide P3 rejuvenates by biomimetic exfoliation
The connection of cells is realized by desmosomes. Desmocollin and desmoglein, proteins of desmosomes, bind together at specific sites. PerfectionPeptide P3 contains a tripeptide that consists of the three central amino acid residues of the binding sequence of one of these proteins. Once PerfectionPeptide P3 is applied it impairs the binding of adjacent cells. As a consequence, cells in the stratum corneum lose contact possibilities with neighboring cells and start to peel off.

PerfectionPeptide P3 leads to a gentle peeling
For optimal penetration, PerfectionPeptide P3 is encapsulated into liposomes. PerfectionPeptide P3 stimulates the natural desquamation process of the skin leading to a gentle biomimetic peeling. Consequently, a brighter, smoother, and even-toned skin complexion is created. Your skin is rejuvenated and appears younger.


Is there proof of efficacy for PerfectionPeptide P3?

A cream containing 1% PerfectionPeptide P3 was applied for 17 days. Then the skin surface was analyzed with scanning electron microscopy.

A rough skin surface is characterized by eruptive layers and a broad distance between layers as seen on the left side. The skin treated with PerfectionPeptide P3 clearly showed a smoother surface at the end of the study (figure on the right).