Progeline™

Functions
Anti-aging
Lifting
Firming

Progeline™ (Trifluoroacetyl Tripeptide-2; sequence: TFA-Val-Try-Val-OH) is a biomimetic peptide-based complex ingredient that mimics a specific protein Elafin responsible for the inhibition of the Elastase enzyme that breaks down elastin. Preserving elastin prevents skin sagging and the development of wrinkles allows achieve a complete remodeling effect.

This tripeptide leaves a regulatory effect on the ECM (extracellular matrix) protein quantities and protects the integrity, fighting against gravitational and mechanical factors of skin aging. Lessening progerin (damaged version of dermal Lamin A protein - aging biomarker) production, Trifluoroacetyl Tripeptide-2 slows down the senescence of skin cells. It visually decreases the appearance of signs of aging and skin maturation smoothing fine lines and deep wrinkles, and fighting against slackness and sagging.

The reduction of progerin production has been proved by a series of lab and clinical studies. In the laboratory, progerin was quantified in cell lysates of mature skin fibroblasts (that were incubated for 96 hours) using the ELISA method, which showed a significant reduction. Clinical trials proved its antiaging effects including jawline lifting action, and improvement of skin firmness and elasticity. Progeline™ has an overall satisfaction score of 92% as consumers agree that it helps the skin to look firmer, fuller, and denser.

Active ingredients (or INCI)

Glycerin
Aqua (Water)
Dextran
Trifluoroacetyl Tripeptide-2

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