DermaPep™ WrinCare

Functions
Firming
Smoothing
Anti-aging

Collagen represents the main component of the extracellular matrix of the dermal connective tissue and its concentration decreases as we age. It is known that the loss of collagen is not only due to a reduction of the synthesis but also due to its enhanced degradation. The enzymes called MMPs are mainly responsible for collagen breakdown and inhibition of new collagen formation in the skin.

Transforming growth factor (TGF-β), a member of a large family of secreted peptide growth factors is known to play a prominent role in the accumulation of ECM (extracellular matrix) components by increasing the expression of ECM genes, such as collagen, elastin, fibronectin, and proteoglycan.

DermaPep™ WrinCare is a peptide-based complex with a rejuvenating, anti-aging effect. It is a mixture of TGF beta mimic myristoyl tetra-peptide and MMP-1 inhibitor myristoyl tetra-peptide, effectively boosts the procollagen production and strongly inhibits MMPs which are collagen degrading enzymes under normal or UV irradiated conditions.

In vitro studies show that procollagen production is performed via TGF-beta signaling by myristoyl tetrapeptide-6 and MMP-1 is inhibited via AP-1 de-activating pathway by myristoyl tetrapeptide-34.

These two peptides show additional effects on human skin aging by working respectively. The clinical study also shows that each of the peptides has a brilliant effect on reducing wrinkles.

Active ingredients (or INCI)

Related ingredients

Acetyl Dipeptide-1 Cetyl ester
Acetyl Dipeptide-1 Cetyl ester
This lipopeptide exhibits good stimulating results on elastin production. As a result, Acetyl Dipeptide-1 Cetyl ester fights against cutaneous sagging and decreases the visible effects of gravity on the skin.
Acetyl Heptapeptide-9
Acetyl Heptapeptide-9 mimics the TGFβ. Acetyl Heptapeptide-9 effects on fibroblasts, stimulating collagen, elastin, and other components of ECM production.
Acetyl octapeptide-3
Acetyl octapeptide-3
Acetyl Octapeptide-3 is a brilliant, new, deep penetrating, powerful amino-peptide with a fantastic ‘BOTOX® like’ effect.
Acetyl Tetrapeptide-5
Acetyl Tetrapeptide-5
Acetyl Tetrapeptide-5 is a fantastic, super effective, naturally derived tetrapeptide that helps reduce the look of puffy eye bags and dark circles under the eyes and helps prevent them from reappearing.
Acmella Oleracea Extract
Acmella Oleracea Extract
Acmella Oleracea is an exotic plant, also known as Paracress. In the Indian Ocean region, it is called "Mafane". Reduces facial muscle micro-contractions, smoothes and reduces lines and wrinkles.
Acnacidol™ BG
Acnacidol™ BG
Acnacidol™ BG is a clinically tested complex that contains Queen bee acid (10-HDA or 10-Hydroxydecanoic Acid found in Royal Jelly that controls and reduces sebum and the appearance of acne.
Adenosine 5 Triphosphate (ATP)
Adenosine 5 Triphosphate (ATP)
Naturally existing in our bodies as part of the molecule adenosine triphosphate (ATP), responsible for transporting energy for numerous cellular and muscular functions in our body
Alistin®
Alistin®
Alistin® (Decarboxy Carnosine) is a synthetic antiaging pseudodipeptide with high stability and resistance to enzymatic hydrolysis, that cell membranes oxidative stress and dermal fiber from cross-linking.
Alpha-Glucan Oligosaccharide
Alpha-Glucan Oligosaccharide
Thanks to the specificity of its inter-glycosidic bonds, Alpha-Glucan is a selective substrate for the nutrition and development of the skin's saprophytic (beneficial) flora to the detriment of undesirable opportunists flora (pathogenic or not) ready to invade the skin at the slightest sign of imbalance.
AquaCacteen™
AquaCacteen™
AquaCacteen™ is a botanical complex based on the Barbary fig stem extract and designed to soothe and calm irritated skin, protect from environmental stress factors, and deeply hydrate with long-lasting effects.
Argireline®
Argireline®
Acetyl Hexapeptide-8 is a mimic of the N-terminal end of SNAP-25. It competes with the natural protein for a position in the SNARE complex and relaxes facial muscles, destabilizing its formation without breaking any component.
Ascorbyl Tetraisopalmitate
Ascorbyl Tetraisopalmitate
Like other forms of Vitamin C, Ascorbyl Tetraisopalmitate helps prevent cellular aging by inhibiting the cross-linking of collagen, oxidation of proteins, and lipid peroxidation.