Oligopeptide-177

Oligopeptide-177 is a synthetic peptide with 33 amino acids whose sequences repeat a fragment of the erythropoietin (EPO) glycoprotein. EPO's main function is the stimulation of blood red cells (erythrocytes) production, but it has other functions including the promotion of tissue regeneration and cell protection (prevents apoptosis or cell self-destruction).

Thanks to a specific structure (sequence), Oligopeptide-177 does not affect hematopoietic (blood cell production) processes but kept other beneficial functions that are in demand in modern skincare applications. After topical application, it can bind to a specific receptor CD90 on skin keratinocytes and fibroblasts, promoting skin regeneration, renewal, and wound healing. In clinical trials, Oligopeptide-177 exhibited significant beneficial effects against signs of skin aging, acne, and UV-induced irritation. It is one of the active ingredients in the patented complex TFC8® (Trigger Factor Complex) by Augustinus Bader where it plays a major role.

Functions
Anti-aging
Anti-wrinkle

Related ingredients

Acetyl Dipeptide-1 Cetyl ester
Acetyl Dipeptide-1 Cetyl ester
This lipopeptide exhibits good stimulating results on elastin production. As a result, Acetyl Dipeptide-1 Cetyl ester fights against cutaneous sagging and decreases the visible effects of gravity on the skin.
Adenosine 5 Triphosphate (ATP)
Adenosine 5 Triphosphate (ATP)
Naturally existing in our bodies as part of the molecule adenosine triphosphate (ATP), responsible for transporting energy for numerous cellular and muscular functions in our body
Alistin®
Alistin®
Alistin® (Decarboxy Carnosine) is a synthetic antiaging pseudodipeptide with high stability and resistance to enzymatic hydrolysis, that cell membranes oxidative stress and dermal fiber from cross-linking.
Ascorbyl Tetraisopalmitate
Ascorbyl Tetraisopalmitate
Like other forms of Vitamin C, Ascorbyl Tetraisopalmitate helps prevent cellular aging by inhibiting the cross-linking of collagen, oxidation of proteins, and lipid peroxidation.
Bakuchiol
Bakuchiol
Bakuchiol is a derivative from the psoralea corylifolia plant used in oriental medicine. The first natural alternative to retinol.
Biopeptide EL™
Biopeptide EL™
Biopeptide EL™ is a peptide-based complex ingredient for skin firmness and tone improvement. Palmitoyl Hexapeptide-12 is a synthetic lipo-peptide, a derivative of VGVAPG-peptide with the sequence Val-Gly-Val-Ala-Pro-Gly which is a fragment of the natural elastin.
Caprooyl tetrapeptide-3
Caprooyl tetrapeptide-3
Caprooyl tetrapeptide-3 is a biomimetic lipopeptide structure based on TGF-ß (transforming growth factor beta) that plays an essential role in the natural production of the extracellular matrix components.
Ceramide II (NG)
Ceramide II (NG)
Ceramide II (NG), also known as N-stearoylsphinganine or Ceramide 2, is similar to dermal cells' membrane molecules. It renews the skin't lipid layer, reduces transdermal moisture loss, and improves water-binding ability.
Creatine
Creatine
Creatine is an amino acid derivative (non-proteinogenic amino acid) found naturally in the skin. It acts as an energy reservoir essential for the energy supply and function of the cells, participating in ATP production, which is a universal fuel molecule.
ChroNoline™
ChroNoline™
CroNoline™ is a specially formulated amino acid combination, which recreates growth factors found in youthful skin.
Damask Rose Oil
Damask Rose Oil
This adorable oil has antimicrobial, antioxidant, anti-inflammatory, and anti-aging effects. Rosa damascena has a wide spectrum of antimicrobial activities against many species of harmful bacteria. Like many other aromatic and medicinal flowers, it shows antioxidant properties.
Dermaxyl™
Dermaxyl™
Ceramide 2 replenishes the lipid barrier and improves the skin's water-binding ability, smoothing fine lines and deep wrinkles. Palmitoyl Hexapeptide-12 stimulates fibroblasts' mobility and boosts elastin production, improving skin elasticity and firmness.