Saccharide Isomerate

Functions
Humectant
CAS Number(s)
100843-69-4
FDA UNII
W8K377W98I
INCI name
Saccharide Isomerate

Saccharide isomerate is a product of isomerization of plant-derived D-glucose that increases the water-binding capacity of the stratum corneum, adheres to the keratin of the horny layer, and reduces dryness and irritation caused by Alpha Hydroxy Acids (AHAs).

Prolonged hydration

Thanks to the natural structure and composition, saccharide isomerate serves as a very effective moisture regulator providing prolonged water retention in the skin. It binds to the stratum corneum's keratin on free amino groups of lysine. This unique binding mechanism provides a special and natural affinity to the skin while improving barrier function and preventing washing out from the surface and long-lasting effects. Therefore, the saccharide isomerate remains in the epidermis until natural desquamation.

Hyaluronic acid production

Stimulating fibroblasts, Saccharide isomerate promotes the production of hyaluronic acid (HA) up to 66%, supporting hydration and improving skin volume and density. Increased HA production smooths fine lines and deep wrinkles, revealing a youthful, supple, and fresher appearance.

Probiotic

Saccharide isomerate exhibits an extraordinary and selective probiotic effect, promoting the growth of beneficial microorganisms like Paracoccus Marcusii. This organism produces Beta-carotene, a superstar carotenoid with numerous positive functions for the skin. Furthermore, it suppresses the growth of harmful bacteria, changing microbiota equilibrium to a better state and exposing a healthy, naturally beautiful, and glowing appearance.

Ingredient products

Tissue Activator Serum
MBR® Medical Beauty Research
Gentle Moisturizing Gel
MBR® Medical Beauty Research
Travel Set Tissue Activator
MBR® Medical Beauty Research
Masque VIP O2
Biologique Recherche
PRIMARY SERUM
Valmont
CLARIFYING PACK
Valmont
V-LINE LIFTING CONCENTRATE
Valmont
V-LINE LIFTING CREAM
Valmont
Complete Anti-Pollution Spritz
Environ

Composition of the neutral carbohydrate fraction found in the human stratum corneum compared to the carbohydrate complex Saccharide Isomerate

 human stratum corneumsaccharide isomerate
Psicose0.2%0.5%
Glutose2.2%0.2%
Mannose3.0%3.6%
Fructose31.1%37.0%
Glucose46.7%53.3%
Galactose2.1%1.3%
Various14.7%4.1%

Comparison with other humectants

Comparative tests with classic moisturizer ingredients like glycerin and urea showed higher saccharide isomerate effectiveness. Moreover, it effectively prevents transdermal water loss in lower relative humidity conditions.

Prolonged moisture-binding and long-lasting hydration make this sugar complex ideal for almost all skincare formulas, especially cleansing applications and chemical peels. In addition, this "water magnet" is a functional moisturizer that protects dry skin and prevents classic issues like roughness, unevenness, and itching.

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