Skin conditioning

In skin care, conditioning is everywhere. Consumers have always wanted their skin moisturized, nourished, restored, and protected. Each of these benefits results from the activity we call conditioning.

Here are some of the most intriguing products for providing conditioning effects. They have performance properties offering "extraordinary" conditioning for the skin.

These are specialty ingredients that create memorable, distinctive features in skincare products – the kind of features that will help offerings stand out in the minds of customers.

From phospholipids to quaternaries, the products in the line are based on exceptionally creative chemistry, making them ideal ingredients for today's personal care products. Features such as mildness, substantivity, high performance, and multifunctionality are common in modern skin conditioners.

Palmitoyl Dipeptide-10 is a synthetic lipopeptide (Sequence Pal-Ala-His) with Carnosine-like action. It is also known under the trade names SunPEP Di-100 and C-Pep™.

Palmitoyl Dipeptide-52 is a simple lipopeptide with sequence Pal-Pro-Pro known under the trade name Silverfree™ developed by Sederma. It is a pro-pigmenting peptide that stimulates the repigmentation of hair.

An innovative peptide binds neurons and blocks the neuromuscular connection, providing a Botox-like effect with minimal concentrations and without injections.

Palmitoyl Heptapeptide-27 is a synthetic biomimetic lipo-peptide that boosts the production of filaggrin and loricrin proteins involved in barrier function and many other processes in the skin including natural moisturizing factors (NMF) production, pH balancing, and homeostasis.

Palmitoyl Hexapeptide-12, also known as Biopeptide El™, is a conjugate of Palmitic acid and a peptide with a sequence Val-Gly-Val-Ala-Pro-Gly, known as a fragment of the protein called elastin.

Palmitoyl Hexapeptide-14 (former Palmitoyl Hexapeptide-6) is a short bioactive peptide with a lipid delivery system for deeper penetration into the skin. It is an anti-aging lipo-peptide that stimulates skin the proliferation of dermal fibroblast cells boosting collagen production.

Palmitoyl Hexapeptide-52 is a synthetic lipopeptide that inhibits acetylcholine release into the synaptic cleft and expression muscle contractions.

Palmitoyl Octapeptide-24 is a synthetic guiding lipo-peptide that can bind to specific receptors on keratocytes like a key and lock.

Palmitoyl Octapeptide-26 stimulates collagen and elastin production, enhancing the effectiveness of Heptapeptide-15 palmitate in FibroBoost® Complex.

Palmitoyl Oligopeptide-78 is a synthetic biomimetic lipo-peptide that stimulates keratin production by keratinocytes, enhancing epidermis thickness, lessening transdermal moisture loss, and enhancing the barrier function of the skin.

Palmitoyl sh-Octapeptide-24 Amide is a lipo-peptide derived from palmitic acid and a synthetic analog of a human peptide that inhibits the expression of genes responsible for tyrosinase enzyme production. The Lipophile part (palmitic) provides stability and improves delivery.

Palmitoyl sh-Tetrapeptide-2 Amide is a lipo-peptide that inhibits interleukin-1R, an inflammatory cytokine receptor, soothing skin irritation and acting as an anti-inflammatory agent. It is known under the trade name Ilonerin™.

Palmitoyl sh-Tripeptide-1 Amide is a low molecular weight synthetic recombinant lipo-peptide derived from FGF-1 (fibroblast growth factor -1) that is involved in various cellular processes, including angiogenesis, keratinocyte organization, and wound healing.

Palmitoyl sh-Tripeptide-2 Amide is a low molecular weight lipo-peptide derived from Tumor Necrosis Factor Receptor (TNFR) that inhibits TNF-α ( tumor-necrosis factor-α). It is known under the trade name Tenefrin™.

Palmitoyl sh-Tripeptide-3 Amide is a low molecular weight lipo-peptide derived from Epidermal Growth Factor (EGF) that stimulates cell growth, proliferation, and differentiation by binding to its receptor EGFR. It is also known under the trade name Synepin™.

Palmitoyl sh-Tripeptide-4 Amide is a low molecular weight lipo-peptide (316.3 Da) derived from CD99, an anti-inflammatory molecule that is expressed in all human cells. It is also known under the trade name Binterin™.

Palmitoyl Sh-Tripeptide-5 Norisoleucyl Sh-Nonapeptide-1 is a lipo-peptide that acts as an antagonist of

Palmitoyl Tetrapeptide-7 (also known as Rigin™) is a lipopeptide from Sederma designed to mimic DHEA activity and restore cytokine balance to mature skin.

Palmitoyl Tetrapeptide-72 Amide is a synthetic lipo-peptide with sequence Pal-His-Tyr-Arg-Ala-NH2 that boosts expression and production of Mohawk, a homeodomain protein abundantly expressed in the young skin and actively involved in the regeneration of EMC components and connective tis

Palmitoyl Tripeptide-1 stimulates fibroblasts and enhances the production of collagen and GAGs, smoothing fine lines and deep wrinkles and improving the water-binding ability and elasticity of the skin.

Palmitoyl tripeptide-28 is a peptide ingredient based on TGF-β (Transforming growth factor beta) that mimics cytokine action by binding with specific receptors (TGF beta receptor 2) on fibroblast membrane, stimulating the production of extracellular matrix (ECM) components.

Palmitoyl Tripeptide-36 is a synthetic lipo-peptide known under the trade name DermaPep™ M330 that exhibits anti-microbial activity. It inhibits the growth of Staphylococcus aureus and other bacteria, and fungi. Peptide sequence is Palmitoyl-Lys-Met(O2)-Lys-OH.

Palmitoyl Tripeptide-37 is a synthetic lipo-peptide with sequence Pal-KFK (Palmitoyl-Lys-Phe-Lys) that leaves thrombospondin-like action. It is an analog of Lipospondin. It is an ester of palmitic acid and Tripeptide-37 (KFK peptide) with an active Thrombospondin domain sequence.

Palmitoyl Tripeptide-38 also known as Pal-KMO2K is a matrikine-mimetic peptide, that stimulates hyaluronic acid and collagen production.

Palmitoyl Tripeptide-53 Amide (known under the trade name Winhibin™) is a low molecular-weight tripeptide derived from Sfrp5 (Secreted frizzled protein5) and known as a modulator adipokine of WNT-signaling.

Panthenol is a provitamin of Pantothenic acid (vitamin B5), part of the B-complex group, is present in all living cells and is a constituent of coenzyme A. The critical function of this coenzyme is to act as a carrier in acetylation reactions (Krebs cycle).

Vitamin B5 (Pantothenic acid) is a precursor of the coenzymes involved in more than 100 different metabolic pathways including energy metabolism of carbohydrates, proteins, and lipids, and the synthesis of lipids, neurotransmitters, steroid hormones, porphyrins, and hemoglobin.

Papain is produced from the milky latex of all papaya parts but especially in the green, unripe fruits by scarification of the skin of the fruit and inducing latex flow.
Papain, one of the active enzymes in papaya, has antimicrobial properties. Papaya can help reduce edema, may discourage clotting, and promotes wound healing, and the active enzymes also mildly exfoliate the skin.

Paraffin is a class of mineral waxes obtained from the petroleum refining process. It is a white-to-yellowish solid containing straight-chain saturated hydrocarbons, which are predominant in functionality. Based on melting point, paraffin has five different grades, ranging from 120-155ºC.