Peptides

There are numerous examples in physiology of peptide regulatory elements that play integral roles in basic homeostatic mechanisms such as injury-repair responses and other stimulus-response actions. Among these are well-known neuropeptides (e.g., bradykinins, endorphins); metabolism and fat storage regulators (e.g., neuropeptide Y, leptin, insulin); tanning and skin pigmentation-related peptides (e.g., α-MSH, ACTH, Agouti), and peptides involved in wound healing (e.g., FGF).

This large group of innovative cosmeceutical ingredients triumphed in the world of skincare products during the last two decades. Peptides are chains of amino acids that are attached in a specific order. Amino acids are naturally occurring in the body and are vital to everyday living processes. Peptides can be made up of 2 or more amino acids that can stimulate different responses within the body. As a result, peptides serve as tiny messengers that can be sent to kick the skin into gear and make it look better.

Peptides are leading a beauty revolution due to their excellent multi-functional properties; formularies are scrambling to access the latest advances in cosmetic peptide technology. In addition, their "Botox-like" performance, activation of collagen and elastin production, and skin-lightening effect make them very efficient against coarse wrinkles and hyperpigmentation of the skin.

Decarboxy Carnosine
Alistin® (Decarboxy Carnosine) is a synthetic antiaging pseudodipeptide with high stability and resistance to enzymatic hydrolysis, that cell membranes oxidative stress and dermal fiber from cross-linking.
Decorin deposits visualization

Arginine/Lysine Polypeptide is a 40% dry extract solution ( p/p ) composed of L-lysine and L-arginine oligopeptide with a degree of polymerization from 2 to 7, obtained by a solvent-free process enzymatic synthesis.

Argireline® Acetyl Hexapeptide-8
Acetyl Hexapeptide-8 is a mimic of the N-terminal end of SNAP-25. It competes with the natural protein for a position in the SNARE complex and relaxes facial muscles, destabilizing its formation without breaking any component.
Argirelox is a complex that combines the power of two revolutionary peptides fighting against expression lines and deep wrinkles by relaxing facial muscles.
Bipure is an innovative tetrapeptide obtained by condensation from azelaic acid and two molecules of the Dipeptide-10 (alanine-histidine).
Beta-White™ is an innovative biomimetic encapsulated (liposome) whitening peptide Oligopeptide-68 with a significant lightening effect. It reduces skin pigmentation and discolorations as well as age spots
Bio Placenta is a combination of five synthesized growth factors (EGF, IGF-1, acidic FGF, alkaline FGF, VEGF), amino acids and vitamins. Stimulates cell growth and skin tissue repair.
Biopeptide EL™

Biopeptide EL™ is a peptide-based complex ingredient for skin firmness and tone improvement. Palmitoyl Hexapeptide-12 is a synthetic lipo-peptide, a derivative of VGVAPG-peptide with the sequence Val-Gly-Val-Ala-Pro-Gly which is a fragment of the natural elastin.

Biotinoyl Tripeptide-1
Thanks to stimulating peptide that promotes anti-aging processes in the follicle, encouraging anchoring of molecules, supporting hair growth, and slowing down premature hair loss.

BoNT-L peptide (Palmitoyl Hexapeptide-19) is a synthetic lipo-peptide with a Botox-like effect and without the side effects of invasive treatment. In comparison with Botox, it has several advantages such as:

The neurocosmetic or "intelligent cosmetic" is the topic application of active ingredients whose neurophysiologic action offers some cosmetics, esthetic, and wellness benefits. It opens a new generation of active ingredients.

Calmosensine™
Powered with triple-action lipopeptide Acetyl Dipeptide-1 Cetyl ester, Calmosensine™ leaves a significant anti-aging effect, boosting elastin production, mimic-muscle relaxation, and releasing precursor of endorphins (well-being hormones).
Red Clover
Capixyl is a bio-mimetic peptide with a red clover extract. It's an Hair Care Complex with anti-aging properties.
Caprooyl tetrapeptide-3
Caprooyl tetrapeptide-3 is a biomimetic lipopeptide structure based on TGF-ß (transforming growth factor beta) that plays an essential role in the natural production of the extracellular matrix components.

Sensitive skin is often defined by a propensity to sensory responses such as stinging, itching, burning, or visible reactions, such as erythema, papules or vesicles, wheal and flare responses, dryness, scaling, and desquamation, in response to external stimuli.

ß-alanyl-L-histidine

Carnosine is a dipeptide (ß-alanyl-L-histidine) found in the human body. The nature-identical "L" form L-Carnosine is a white odorless powder, soluble in water.

ChroNoline™
CroNoline™ is a specially formulated amino acid combination, which recreates growth factors found in youthful skin.
Formulated to regulate collagen fiber formation, Collagen Regulator Tetrapeptide binds to collagen fibrils to dramatically restore skin suppleness and enhance lift.

Copper Palmitoyl Heptapeptide-14 is a synthetic lipopeptide complex with copper, a core active ingredient in advanced complex X50® Anti-Aging.

GHK-Cu

Numerous skincare products based on copper-peptide complexes are increasingly finding clinical and cosmeceutical uses. The biological basis for these actions is GHK (Tripeptide-1), a peptide generated during tissue damage with a very high affinity for copper (Cu2+).

Copper Tripeptide-1 Palmitamide

Copper Tripeptide-1 Palmitamide is a complex of copper with a synthetic lipopeptide, a modification of the famous GHK peptide (Tripeptide-1) in which terminal lysin's amino group is acylated with palmitic acid.

N-Palmitoyl-Lys-Thr-Phe-Lys

Crystalide™ is a peptide-based complex by Sederma with an illuminating effect from deeper skin layers to the surface. The concept of "Glass Skin" is a very popular trend in modern skincare applications and indicates translucent, hydrated, and luminous skin.

Cyclohexpeptide-90 is a synthetic cyclic hexapeptide that increases BiP and Calreticulin protein production, chaperones in the endoplasmic reticulum responsible for proteins properly folding. This peptide is known under the trade name Poptide™.

Cyclotetrapeptide-24 Aminocyclohexane Carboxylate
RonaCare® Cyclopeptid-5 rapidly gives the skin a fresher and more youthful appearance. The peptide replicates the natural processes of skin communication and repair.

Out of all the trends originating from Asia that have influenced the world, the one that has gained the widest acceptance is the search for "harmony".

D-Arginyl Tyrosinyl Ornithinyl Phenylalanine

D-Arginyl Tyrosinyl Ornithinyl Phenylalanine is a synthetic tetrapeptide with sequence D-Arg-Tyr-Orn-Phe-NH2 similar to Szeto–Schiller (SS) peptides. Szeto–Schiller peptides are tetrapeptides that showed promising results against a wide range of mitochondrial disorders and are con

Decapeptide-10 is a synthetic peptide that boosts the generation of new dermal cells lessening the appearance of fine lines and wrinkles, preventing their formation, and strengthening hair follicles. This peptide is also known under the trade name CG-Keramin2.

Lumixyl™

Decapeptide-12 is a synthetic peptide (with sequence Tyr-Arg-Ser-Arg-Lys-Tyr-Ser-Ser-Trp-Tyr) known under the trade name Lumixyl™ that acts as a tyrosinase inhibitor, the enzyme responsible for the production of melanin in the skin.

Decapeptide-18 is a synthetic peptide known under the trade name CG-WINT that stimulates the formation of a new hair follicle.

Decapeptide-19

Decapeptide-19 is a synthetic peptide with the sequence Ala-Cys-Asp-Gly-Arg-Thr-Gln-Ala-Leu-Cys that inhibits the specific biological activity of TNF-α cytokine and exhibits anti-inflammatory and hair growth-promoting properties. It is known under the trade name CG-Elima.