Anti-acne

The sebaceous gland is one of several glands in the skin usually associated with hair follicles. It produces and secretes sebum through the breakdown of the entire sebaceous cell by lysosomal enzymes.

The sebum is a greasy secretion that lubricates the skin and assists with water retention to prevent dryness. The relatively large glands are present in the face area, where they join to the hair canal at a depth of approximately 0.5 mm below the skin surface. The renewal rate of average-size sebaceous lobules in humans is between 21 and 25 days.

Acne can result from three typical disorders in sebaceous gland functionality:

  • overproduction of sebum,
  • the proliferation of Propionibacterium acnes bacteria,
  • abnormal desquamation of the sebaceous follicle epithelium, leading to a clogged pore.

Anti-acne ingredients act against those conditions, so they can be relatively classified by functionality into three to four groups:
  • sebum-regulating or sebostatic,
  • antibacterial or antiseptics that eliminate Propionibacterium acnes,
  • exfoliants against abnormal desquamation,
  • unclogging ingredients (including exfoliants) such as some enzymes, vitamins, and solubilizers.

Citrus Aurantium Dulcis Juice is derived from Calabrian golden orange juice, rich in vitamin C, and contains vitamins A, B1, B2, B6, H, and PP. It is a yellow to light brown liquid with a characteristic odor and acidic pH of 3.0 - 4.0.

Watercress (Nasturtium officinale) has a long history of medicinal use. High in Vitamin A, It was used to treat eye disorders, excess weight, bleeding gums, arthritis, rheumatism, atherosclerosis, kidney and liver disorders, and internal swelling.

AC.NET™ is a complex that consists of a specific blend of components that together target all the causes and symptoms associated with oily, acne-prone skin, significantly reducing the incidence of breakouts.

Acetyl Dipeptide-3 Aminohexanoate (sequence Ac-Arg-Ala-Ahx-OH) also known under the trade name Bodyfensine® is a tripeptide that boosts the skin's natural peptidic protection against harmful microbes.

Acnacidol™ BG is a clinically tested complex that contains Queen bee acid (10-HDA or 10-Hydroxydecanoic Acid found in Royal Jelly that controls and reduces sebum and the appearance of acne.

Activys® Red-Out is a liposomal complex that targets redness, tackles skin immuno-modulation, and reinforces skin barrier function to help reduce facial flushing and chronic redness, especially in atopic-prone conditions and skin hypersensitivity.

In the Middle Ages, a Lady's Mantle (Alchemilla Vulgaris) was considered sacred to various Earth goddesses and later became the herb of the Virgin Mary. The herb's styptic, tissue-contracting, and astringent properties made it useful for treating wounds and stopping bleeding.

Biopol™ β is a combination of naturally derived materials that helps to control sebum and reduce microbial flora associated with acne blemishes.

Biotin (Vitamin B7) rescues the skin. How? Let’s see. If you do not use it for a while your skin looks dull, it becomes dry, inflammation and wrinkles appear on it, the face ages faster.
Burdock, officially called Arctium lappa, is considered a healthy and nutritive food in China. Arctium lappa was used as a medicinal herb in Europe, North America, and Asia for centuries.

Cytobiol™ Iris A is a botanical-vitamin-mineral complex with synergistic action of ingredients.

American Indians used Witch Hazel (Hamamelis Virginiana) in skin solutions and applied compresses externally to soothe inflammations, burns, infections, inflamed eyes, and body aches.

Herbasec® MPE Sebostat is composed of three plant extracts specially chosen for their sebum-regulating properties. Independent laboratory data support its efficacy.

Hexacarboxymethyl Dipeptide-12 is a peptide derivative that acts as a direct activator of Sirtuin1 (SIRT1). SIRT1 is an NAD+-dependent deacetylase enzyme that regulates cellular metabolism, survival, and lifespan. It deacetylates the target protein FoxO1, initiating cell autophagy.

In skin care preparations Horseradish root extract fights against acne and other mibobe-induced conditions, while acting as a natural preservative enhancing the shelf-life of the product.

Hydroxypinacolone Retinoate is a pure ester form of Tretinoin (all-trans-Retinoic acid) that works similarly to Retin-A but without the irritation of Tretinoin.

In traditional medicine, Hyssopus officinalis has the properties of a cleanser, both in and out of the body. The leaves hold an antiseptic and antiviral oil, and their leaves possess the same kind of fungus that produces penicillin.

InvisaSkin®-64 Anti-Acne Treatment is a peptide-based complex a unique combination of hydrating delivery vehicle, anti-microbial peptide, and salicylic acid offers a gentle approach to treating the symptoms of acne.

Lactobacillus Ferment Lysate raises keratinocyte proliferation and migration, stimulating natural renewal processes. It soothes UV-induced damage protecting against photoaging and improving barrier function.
Anecdotal successes include Melissa Officinalis successfully used heal an ulcerated spider bite. Melissa preparations are suitable for acne, eczema, cuts, sores, minor wounds, and warts, as well as painful insect bites and bee stings.

Linoleic acid is an essential fatty acid (EFA). EFAs are fundamental constituents of bio-membranes and precursors of biological substances such as prostaglandins, leukotrienes, and hydroxylated fatty acids.

Micrococcus Lysate is an active ingredient of marine origin, natural, safe, and non-irritating for acne treatment and acne-prone skin. It helps relieve blemishes and reduce redness and inflammation without typical acne ingredients' harsh, drying,
irritating effects.

Myristoyl hexapeptide-23 is a synthetic lipo-peptide with antibacterial properties against Propionibacterium acnes (Cutibacterium acnes).

Myristoyl Octapeptide-1 is a synthetic lipo-peptide that mimics growth factors, promoting dermal tissue repair processes and accelerating wound healing. It binds to the specific receptors on fibroblasts, boosting skin cell proliferation and activity.

Myristoyl Tetrapeptide-13 is a synthetic cationic lipopeptide with a potent antimicrobial activity. It is designed to work alone or in synergy with other antibacterial agents to act as an anti-acne active or performance-enhancing preservative.

Myrrh Resin Extract is an oil obtained by extracting Commiphora Abyssinica (Commiphora Myrrha) tree resin valued for antiseptic, anti-inflammatory, and astringent properties.

Oligopeptide-10 is a 15-amino-acid-long peptide with the sequence Phe-Ala-Lys-Ala-Leu-Lys-Ala-Leu-Leu-Lys-Ala-Leu-Lys-Ala-Leu. It is a water-soluble white powder, compatible with all emulsion types in the 5-7 pH range.

Oligopeptide-76 is a synthetic biomimetic 13 amino acid long peptide, an analog of natural Aurein 1.2 peptide produced in the skin of the Litoria Aurea frog.

The onion bulb contains many biologically active components, including vitamins and provitamins, amino and fatty acids, and antioxidant phytosterols.