sh-Nonapeptide-4 is a synthetic recombinant peptide known under the trade name Clodessine, a fragment of human Klotho protein that activates different Fibroblasts Growth Fatrors (FGF) and is related to lognitivity. Klotho is considered to be an anti-aging factor.
Skin conditioning
In skin care, conditioning is everywhere. Consumers have always wanted their skin moisturized, nourished, restored, and protected. Each of these benefits results from the activity we call conditioning.
Here are some of the most intriguing products for providing conditioning effects. They have performance properties offering "extraordinary" conditioning for the skin.
These are specialty ingredients that create memorable, distinctive features in skincare products – the kind of features that will help offerings stand out in the minds of customers.
From phospholipids to quaternaries, the products in the line are based on exceptionally creative chemistry, making them ideal ingredients for today's personal care products. Features such as mildness, substantivity, high performance, and multifunctionality are common in modern skin conditioners.sh-Oligopeptide-1 is a synthetic analog of human polypeptide EGF (Epidermal Growth Factor) that contains 53 amino acids. EGF is found in varying concentrations in milk, saliva, urine, plasma, and also in most other body fluids.
sh-Oligopeptide-2 is a synthetic single chain (7.6 kDa) polypeptide hormone structurally similar to proinsulin, which is an Insulin-like Growth Factor (IGF-1) naturally synthesized in the liver and fibroblast cells.
sh-Oligopeptide-4 is a synthetic recombinant Thymosin-β4 peptide that helps strengthen hair while stimulating hair follicles to produce healthier hair.
sh-Oligopeptide-5 is an N-terminal fragment of human AIMP1 (ARS-interacting multi-functional protein 1).
sh-Pentapeptide-1 (former designation: Pentapeptide-1) is a synthetic recombinant peptide derived from thymopoietin, a human hormone with immunomodulating properties.
sh-Pentapeptide-5 is a synthetic recombinant peptide that mimics endorphin action and leaves a Botox-like effect. This opioid peptide effectively reduces the appearance of expression lines and deep wrinkles exposing smoother, younger-looking, and healthy skin.
sh-Polypeptide-1 is a single-chain synthetic peptide (molecular weight 17.25 kDa) hormone bFGF (basic Fibroblast Growth Factor) that regulates skin's renewal promotional subtraction It is also an essential constituent for maintaining the best condition of the body as this is concerned with restor
sh-Polypeptide-10 is a synthetic recombinant single-chain peptide, an analog of human Fibroblast Growth Factor 10 (FGF10) that is involved in normal skin growth, regeneration, and wound repair.
sh-Polypeptide-12 is a synthetic recombinant single-chain peptide, an analog of human Interleukin 4 (IL-4) that plays the role of an anti-histamine or immune-suppressor agent to reduce scratching by inhibiting the autoimmune response.
sh-Polypeptide-121 is a synthetic single-chain recombinant peptide derived from human collagen type 21 (also called collagen alpha-1 and encoded by the COL21A1 gene). It is known under the trade name HumaColl™21.
sh-Polypeptide-19 (former rh-Oligopeptide-3) is a synthetic single-chain recombinant peptide, an analog of human TGF-α (Transforming Growth Factor-α). It boosts new dermal cell generation improving skin tone that brimming with vitality & energy.
sh-Polypeptide-2 is a synthetic recombinant analog of human Thioredoxin (TRX) that stimulates dermal cell growth and proliferation and protects them from oxidative stress. Thioredoxin is a natural cytoprotector peptide present in all human cells.
sh-Polypeptide-22 is a synthetic recombinant human transforming growth factor beta 1 (TGFβ-1) analog peptide composed of 113 amino acids.
sh-Polypeptide-3 (former rh-Oligopeptide-5) is a single-chain synthetic recombinant peptide, an analog of human KGF (Keratinocyte Growth Factor). KGF was first described in 1989 as a human growth factor that stimulated epithelial cell proliferation.
sh-Polypeptide-31 is a synthetic recombinant peptide that mimics human Insulin-like Growth Factor-2 (IGF-2). The old designation was rh-Polypeptide-31 (rh- prefix means recombinant human).
sh-Polypeptide-4 is a synthetic analog of human SCF (Stem cell factor), a peptide of 164 amino acids. It is a cytokine that controls the survival, growth, and differentiation of hematopoietic stem cells.
sh-Polypeptide-40 is a synthetic recombinant human placental lactogen (hPL) analog peptide composed of 192 amino acids. hPL is also known as human chorionic somatomammotropin (hCS) or human chorionic somatotropin.
sh-Polypeptide-5 is a synthetic recombinant peptide, an analog of human TGFβ3 (Transforming Growth Factor β3). It regulates the proliferation, growth, and differentiation of skin cells as a powerful multifunctional cytokine and keeps the skin young by converting old cells into new ones.
sh-Polypeptide-6 is a synthetic recombinant single-chain peptide, an analog of human Interleukin 10 (IL-10). Interleukin 10 is an anti-inflammatory cytokine that regulates the immune response and antibody production.
sh-Polypeptide-64 is a synthetic recombinant peptide derived from the human Aquaporin-1 (AQP-1) protein that promotes the transport of water biological membranes. AQP-1 is normally expressed in dermal cells, including keratinocytes, melanocytes, fibroblasts, and vascular endothelial cells.
sh-Polypeptide-71 (former sh-Polypeptide-65) is a synthetic recombinant human vasoactive intestinal peptide or VIP composed of 28 amino acids. This biologically active peptide controls vasodilatation in skin tissue, soothes inflammation, and improves angiogenesis.
sh-Polypeptide-8 is a synthetic single-chain recombinant analog of human PDGF (Platelet-Derived Growth Factor) that is involved in normal skin growth, healing, and wound repair.
sh-Polypeptide-9 is a synthetic recombinant analog of human VEGF (Vascular Endothelial Growth Factor). It enhances the division and migration of cytokine by increasing the permeation of serum protein in the capillary vessels.
sh-Polypeptide-93 is a synthetic recombinant human connective tissue growth factor (CTGF) analog peptide composed of 324 amino acids. It mimics an Insulin-like Growth Factor (IGF)-binding domain of CTGF regulating the expression of genes responsible for collagen production in fibroblasts.
Shea butter is a constituent of the choice of numerous leave-on skin, scalp, and hair care formulations. It is semi-solid, buttery oil derived from Shea tree kernels.
Shikimic Acid is a natural polyhydroxy acid (PHA) obtained from Japanese star anise (Illicium Verum; also called Shikimi). It is a multifunctional active ingredient that promotes cell renewal and exhibits antioxidant and antimicrobial activities.
Shorea Stenoptera Seed Butter is obtained from the fruit of the Sal tree (Shorea Robusta). The butter is extracted, further processed, and refined from its fruit to obtain a light-colored yellow butter with a low odor and smooth texture suitable for cosmetics and toiletries.
Silk Amino Acids is a mixture obtained from pure silk fibers by hydrolysis to their free amino acids under carefully controlled conditions. The principal amino acids in this ingredient are glycine, alanine, and serine.
Silk tree extract is also known as Albizia Julibrissin bark extract has antioxidant, anti-aging, and immunostimulating properties, thus used in many skincare formulations.