Peptides

There are numerous examples in physiology of peptide regulatory elements that play integral roles in basic homeostatic mechanisms such as injury-repair responses and other stimulus-response actions. Among these are well-known neuropeptides (e.g., bradykinins, endorphins); metabolism and fat storage regulators (e.g., neuropeptide Y, leptin, insulin); tanning and skin pigmentation-related peptides (e.g., α-MSH, ACTH, Agouti), and peptides involved in wound healing (e.g., FGF).

This large group of innovative cosmeceutical ingredients triumphed in the world of skincare products during the last two decades. Peptides are chains of amino acids that are attached in a specific order. Amino acids are naturally occurring in the body and are vital to everyday living processes. Peptides can be made up of 2 or more amino acids that can stimulate different responses within the body. As a result, peptides serve as tiny messengers that can be sent to kick the skin into gear and make it look better.

Peptides are leading a beauty revolution due to their excellent multi-functional properties; formularies are scrambling to access the latest advances in cosmetic peptide technology. In addition, their "Botox-like" performance, activation of collagen and elastin production, and skin-lightening effect make them very efficient against coarse wrinkles and hyperpigmentation of the skin.

sh-Polypeptide-8 is a synthetic single-chain recombinant analog of human PDGF (Platelet-Derived Growth Factor) that is involved in normal skin growth, healing, and wound repair.

sh-Polypeptide-9 is a synthetic recombinant analog of human VEGF (Vascular Endothelial Growth Factor). It enhances the division and migration of cytokine by increasing the permeation of serum protein in the capillary vessels.

sh-Polypeptide-93 is a synthetic recombinant human connective tissue growth factor (CTGF) analog peptide composed of 324 amino acids. It mimics an Insulin-like Growth Factor (IGF)-binding domain of CTGF regulating the expression of genes responsible for collagen production in fibroblasts.

Shield Bact is a Cationic Host Defense Peptide (CHDP), a hexapeptide with antimicrobial action. It exhibits a broad spectrum of rapid bactericidal activity with a low propensity for resistance development.

Acetyl octapeptide-3

Several factors are involved in skin aging, such as molecular mechanisms related to collagen and elastin proteins degradation, and lipid content in the skin. It has been clearly demonstrated that these factors can be minimized by decreasing facial muscle contraction.

Wasp Spider

sr-(Wasp Spider Polypeptide-1 Oligopeptide-178) is a single-chain recombinant polypeptide that repeats a part of spider silk protein. It is a white soft powder, a product of fermentation using gene-modified yeast in a nutrient-rich medium.

Dipeptide Diaminobutyroyl Benzylamide Diacetate - Syn-Ake
Syn-Ake - immediate smoothing of the skin, thanks to a remodeled tripeptide, originally derived from snake poison, Waglerin-1, which reduces muscle contractions by up to 80 % (in-vitro results), owing to the disabling of the mnACh-receptor.
Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate
Syn®-Hycan prevents sagging skin by boosting existing hyaluronan levels and by improving collagen quality as well as protein performance.
Syn®-Coll (Palmitoyl Tripeptide-5)

Syn®-Coll (Palmitoyl Tripeptide-5) is a patented lipo-tripeptide-based complex based on many years of experience synthesizing peptides for the pharmaceutical industry. It is a small peptide with a unique sequence Lys-Val-Lys to mimic the human body's mechanism to produce collagen via TGF-β.

Syn®-Tacks Before / After 56 days of treatment

Helping skin to behave in a healthy way is the major target of cosmetic research.

GEKG-peptide

Tetrapeptide-21 (GEKG-peptide) is a synthetic peptide that repeats a part of a sequence (Gly-Glu-Lys-Gly) of several extracellular matrix (ECM) proteins such as collagens I, II, III, IV, V, elastin, and pro-elastin.

Chronogen

Our skin has an essential regulatory function, which activity depends on the circadian rhythm. It activates cellular defense processes in the skin during daylight and deactivates during night.

peptide PKEK

Tetrapeptide-30 is a synthetic peptide PKEK (sequence: Pro-Lys-Glu-Lys) that contains a KEK (Lys-Glu-Lys) motif found in antimicrobial polypeptide cathelicidin which can reduce post-inflammatory or UV-induced hyperpigmentation.

CG-Hairstin

Tetrapeptide-53 is a synthetic peptide with sequence Ile-Tyr-Phe-Tyr and hair-growth-promoting activity. It is known under the trade name CG-Hairstin.

Acetyl Tetrapeptide-2

Thymulen®4 is a biomimetic peptide that mimics thymopoietin 

TIMP Peptide is an aqueous solution of matrix metalloproteases inhibiting lipo-peptide designed to decelerate photoaging.

Tranexamoyl Dipeptide-22

Tranexamoyl Dipeptide-22 is a synthetic tripeptide with sequence Txa-Val-Ser (Tranexamil-VS; TXA-VS) that exhibits skin whitening activity. It inhibits the activity of tyrosinase, one of the critical enzymes involved in melanin production.

Tranexamoyl Dipeptide-23

Tranexamoyl Dipeptide-23 is a synthetic tripeptide with sequence Txa-Pro-Ser (Tranexamil-PS; TXA-PS) found by screening α-MSH (α-Melanocyte-Stimulating Hormone) inhibitory activity of Tranexamic acid derivative peptides.

Tridecapeptide-1 is a biochemically designed, high-performing 3D folded peptide with a spherical structure. It rapidly penetrates and binds the acetylcholine receptors responsible for neuromuscular signal transfer, leaving a Botox-like effect.

Tripeptide-1
An RCS scavenger helps prevent visible signs of premature aging from pollution and photo-aging. Tripeptide-1 is also a signaling peptide that stimulates the synthesis of extracellular matrix components, primarily collagen, hyaluronic acid, and other GAGs.
Tripeptide-10 Citrulline
Tripeptide-10 Citrulline is a brilliant new collagen organizing tetrapeptide that mimics decorin, improving collagen structures and restoring the skin's suppleness and resiliency.
Glycyl-L-prolyl-3-hydroxy-L-proline

Many researchers determined that some collagen protein fragments (peptides) enhance collagen production. A short peptide with the Gly-Pro-Hyp sequence is found in collagen structure and protein hydrolysates.

Chronolux

Our body has natural defense mechanisms against environmental damaging factors such as UV exposure, pollution, cigarette smoke, etc, usually affecting daylight hours.

CG-Lipoxin

Tripeptide-41 is a synthetic peptide (sequence Phe-Trp-Tyr) known under the trade name CG-Lipoxin (Lipoxygenase) that delays the accumulation of lipids in the adipocyte and promotes their breakdown into fatty acids. It blocks linoleic acid, which promotes lipid accumulation.

Tripeptide-6 is a synthetic peptide with anti-wrinkle, wound healing, and hydrating properties. This anti-aging peptide is also known under the trade name CG-CTP.

Trojan ® Q10 is an intelligent complex with a dual-targeted delivery system that effectively delivers the CoQ10 to fibroblast mitochondria with pinpoint accuracy.

Acetyl Tetrapeptide-2
Uplevity™ is a peptide invented to fight the undesired effects of a lack of skin firmness and cohesion by enhancing the natural elements that help to maintain collagen levels and elastin fibers correctly assembled, and facilitating the union between cells and the ECM (extracellular matrix).
Vanistryl®
Combination of active peptide-based ingredients encapsulated in a new delivery system (micellar system reconstituted liposome). It acts in the stretch marks already formed and the old ones while preventing the formation of new ones.
Portulaca pilosa plant
Volulip Sederma is an active substance from the essence of the Portulaca pilosa (Kiss me quick) plant, which contains naturally changed matrikines − mimetic peptides − that promote hyaluron synthesis.

X50 Lightening is a liposomal vitamin-peptide complex that intelligently lightens and brightens the skin. It is a skin-whitening agent that inhibits tyrosinase's enzymatic activity, helping lessen dermal pigmentation and even the skin tone.