Sederma

Sederma is a member of the Croda International Group and a worldwide leader in the development of active ingredients for the cosmetic industry.

This lipopeptide exhibits good stimulating results on elastin production. As a result, Acetyl Dipeptide-1 Cetyl ester fights against cutaneous sagging and decreases the visible effects of gravity on the skin.

Aqualance™ has been developed to support normal cell osmoprotectant strategy and ensure optimal water balance in the skin. An estuary is a meeting point between salt water and fresh water, a natural crossroads of a huge variety of fauna and flora beings.

Biopeptide EL™ is a peptide-based complex ingredient for skin firmness and tone improvement. Palmitoyl Hexapeptide-12 is a synthetic lipo-peptide, a derivative of VGVAPG-peptide with the sequence Val-Gly-Val-Ala-Pro-Gly which is a fragment of the natural elastin.

Cellulite is a common term used to describe the accumulation of fat, fluids, and toxins that have been trapped deep in the skin below the epidermal layer, creating a waffled or "orange peel" appearance to the skin.

Crystalide™ is a peptide-based complex by Sederma with an illuminating effect from deeper skin layers to the surface. The concept of "Glass Skin" is a very popular trend in modern skincare applications and indicates translucent, hydrated, and luminous skin.

In order to respond to the new cultural paradigms which associate modernness, performance, and seduction with a firm, slim and glabrous body, cosmetology needs to offer technologically high-performance solutions: the reduction in hairiness is one of the expectations of the new generations who des

Dynalift™ forms an invisible film to smooth the features immediately and lastingly.

For these reasons, Sederma has formulated a new ingredient to help people of 60+ to fortify and restructure their thin and fragile skin.
Evermat™ is a complex based on African yellow wood (Enantia Chlorantha) bark extract that mattifies the complexion and tightens pores.
Haloxyl™ is a peptide complex based on four biologically active molecules, including matrikine lipopeptides Palmitoyl Tripeptide-1 (Pal-GHK) and Palmitoyl Tetrapeptide-7 (Pal-GQPR), iron chelating N-hydroxysuccinimide (NHS), and a flavonoid chrysin, that eliminates under-eye bags and dark circles.
Kelisoft™ delays hair growth and lessens its diameter, decreasing visibility and shaving frequency. Thanks to its anti-inflammatory properties, Kelisoft™ also provides an immediate soothing sensation after hair removal.
Sederma's new ingredient Lumisphere™ an instant and gradual skin brightener.
N-Prolyl Palmitoyl Tripeptide-56 Acetate is a new, innovative, and award-winning peptide that boosts collagen and fibronectin production, improving extracellular matrix structure, fibers organization, and skin density.

Naturally occurring peptides in the skin perform critical roles in skin maintenance and repair, and there is growing interest in harnessing these effects for therapeutic and cosmetic use.

Matrixyl 3000 combines two peptides that help to improve the cellular health of the skin cells, specifically the skin’s extracellular matrix.
Matrixyl™ synthe’6™ is a potent peptide that boosts six skin-rebuilding essentials: macromolecules - proteins and glycosaminoglycans.
A peptide-based wax, activates the protein and proteoglycan synthesis, which increases the density of the connective tissue and tangibly firms the lip‘s contours, moisturizes, restructures.

O.D.A. White™ is a skin-brightening ingredient from the "heart" of the melanocyte with a new mechanism of action. Sederma developed this ingredient to treat skin pigmentation disorders such as freckles, melasma, hyperpigmentation, and the general dark color of ethnic skin.

Ovaliss™ is a complex ingredient that visibly reduces the double chin and reshapes the facial contours. To fight against signs of aging and obesity touching people living in developed countries, Sederma launched an innovative product Ovaliss™ that counteracts the appearance of a double chin.

Pal-KT (Palmitoyl Dipeptide-7) is the shortest matrikine lipo-peptide with anti-aging action that repeats the part of the sequence (palmitoyl-lysine-threonine) of the famous Matrixyl™ pentapeptide (Pal-KTTKS) and exhibits similar properties, boosting extracellular matrix (ECM) components producti

Palmitoyl Dipeptide-52 is a simple lipopeptide with sequence Pal-Pro-Pro known under the trade name Silverfree™ developed by Sederma. It is a pro-pigmenting peptide that stimulates the repigmentation of hair.

Phytosonic™ is a complex herbal anti-cellulite ingredient from Sederma designed to combat fatty tissue hypertrophy by acting on pre-adipocytes and mature adipocytes.
This ingredient based on peptide technology and phytochemistry fights the follicle aging process and prevents hair loss.

Several studies in the 90s showed that on the cellular level stretch marks formation process starts with endogenous glucocorticoid (corticosteroids) secretion under influence of stress or hormonal changes during puberty or pregnancy.

Renovage™ made to extend the skin's youth span and works on the origin of youth and targets the cell actors which guarantee lifespan and youth. The age that we attribute to a face is a global assessment unconsciously based on several visual signs that are additive.

Sederma has demonstrated that Subliskin™'s oligosaccharides have the property to increase hyaluronic acid and its receptor CD44 synthesis but also elastin and laminin-5 synthesis, hence the word "glycokines" (a natural sugar sequence mimicking structurally and functionally oligosaccharide sequence found in the skin).
Sederma has completed a new test on Venuceane™ (a heat-stable biotechnological extract containing Extremozymes™ - Thermus Thermophillus ferment extract) by using for the first time an accelerated skin aging-type process to investigate efficacy on age stability.