Sederma is a member of the Croda International Group and a worldwide leader in developing active ingredients for the cosmetic industry.

Founded in 1964, Sederma introduced many ingredients and technologies that have become well-known and accepted for skin care. Examples include shea butter, cosmetic liposomes, synthetic ceramides, and Matrixyl range peptides.

Sederma was the first company to use microbial fermentation techniques to produce active ingredients that replaced animal tissue extracts. Sederma has developed ingredients for many of the significant international skin-care and cosmetic manufacturers from such work.

Sederma built its reputation as one of the best suppliers in this market segment through its commitment to research and new product development. It has also developed state-of-the-art techniques for testing the performance of its active ingredients, using both clinical trials and highly advanced in vitro methods.
This lipopeptide exhibits good stimulating results on elastin production. As a result, Acetyl Dipeptide-1 Cetyl ester fights against cutaneous sagging and decreases the visible effects of gravity on the skin.

Ancrine™ is a biotechnology-derived complex from Sederma that reduces hair loss by activating the transglutaminases, a group of enzymes known to increase protein reticulation in the scalp and help anchor the hair to the scalp.

Aqualance™ has been developed to support normal cell osmoprotectant strategy and ensure optimal water balance in the skin. An estuary is a meeting point between salt water and fresh water, a natural crossroads of a huge variety of fauna and flora beings.

Biopeptide EL™ is a peptide-based complex ingredient for skin firmness and tone improvement. Palmitoyl Hexapeptide-12 is a synthetic lipo-peptide, a derivative of VGVAPG-peptide with the sequence Val-Gly-Val-Ala-Pro-Gly which is a fragment of the natural elastin.

Cellulite is a common term used to describe the accumulation of fat, fluids, and toxins that have been trapped deep in the skin below the epidermal layer, creating a waffled or "orange peel" appearance to the skin.

Crystalide™ is a peptide-based complex by Sederma with an illuminating effect from deeper skin layers to the surface. The concept of "Glass Skin" is a very popular trend in modern skincare applications and indicates translucent, hydrated, and luminous skin.

In order to respond to the new cultural paradigms which associate modernness, performance, and seduction with a firm, slim and glabrous body, cosmetology needs to offer technologically high-performance solutions: the reduction in hairiness is one of the expectations of the new generations who des

Diacetyl Boldine (DAB) is a derivative of Boldine, an alkaloid initially found in the Boldo (Peumus boldus). It is also known under the Sederma's trade name Lumiskin™.

Dynalift™ forms an invisible film to smooth the features immediately and lastingly.

For these reasons, Sederma has formulated a new ingredient to help people of 60+ to fortify and restructure their thin and fragile skin.

Etioline™ is an ethnobotanical complex from Sederma designed to aid in progressive skin depigmentation. It also fights against hyperpigmentation, dark, and age spots.

Evermat™ is a complex based on African yellow wood (Enantia Chlorantha) bark extract that mattifies the complexion and tightens pores.
Haloxyl™ is a peptide complex based on four biologically active molecules, including matrikine lipopeptides Palmitoyl Tripeptide-1 (Pal-GHK) and Palmitoyl Tetrapeptide-7 (Pal-GQPR), iron chelating N-hydroxysuccinimide (NHS), and a flavonoid chrysin, that eliminates under-eye bags and dark circles.
Kelisoft™ delays hair growth and lessens its diameter, decreasing visibility and shaving frequency. Thanks to its anti-inflammatory properties, Kelisoft™ also provides an immediate soothing sensation after hair removal.

Lipocare™ is a botanical complex that contains a blend of ingredients that synergistically control and reduce the appearance of cellulite - the unsightly pockets of fat that dimple the skin.

Sederma's new ingredient Lumisphere™ an instant and gradual skin brightener.
N-Prolyl Palmitoyl Tripeptide-56 Acetate is a new, innovative, and award-winning peptide that boosts collagen and fibronectin production, improving extracellular matrix structure, fibers organization, and skin density.

Naturally occurring peptides in the skin perform critical roles in skin maintenance and repair, and there is growing interest in harnessing these effects for therapeutic and cosmetic use.

Matrixyl 3000 combines two peptides that help to improve the cellular health of the skin cells, specifically the skin’s extracellular matrix.
Matrixyl™ synthe’6™ is a potent peptide that boosts six skin-rebuilding essentials: macromolecules - proteins and glycosaminoglycans.
A peptide-based wax, activates the protein and proteoglycan synthesis, which increases the density of the connective tissue and tangibly firms the lip‘s contours, moisturizes, restructures.
A blend of three Ayurvedic and Chinese medicinal plant root extracts, Měiritage™ reconnects modern skincare with time-honored practices.

O.D.A. White™ is a skin-brightening ingredient from the "heart" of the melanocyte with a new mechanism of action. Sederma developed this ingredient to treat skin pigmentation disorders such as freckles, melasma, hyperpigmentation, and the general dark color of ethnic skin.

Osmocide™ is a complex with moisturising and preservative-like properties that allows formulators to reduce the level of preservatives in their formulas yet still create safe, long-standing products that resist contamination, as proven by in vitro studies.

Ovaliss™ is a complex ingredient that visibly reduces the double chin and reshapes the facial contours. To fight against signs of aging and obesity touching people living in developed countries, Sederma launched an innovative product Ovaliss™ that counteracts the appearance of a double chin.

Pal-KT (Palmitoyl Dipeptide-7) is the shortest matrikine lipo-peptide with anti-aging action that repeats the part of the sequence (palmitoyl-lysine-threonine) of the famous Matrixyl™ pentapeptide (Pal-KTTKS) and exhibits similar properties, boosting extracellular matrix (ECM) components producti

Palmitoyl Dipeptide-52 is a simple lipopeptide with sequence Pal-Pro-Pro known under the trade name Silverfree™ developed by Sederma. It is a pro-pigmenting peptide that stimulates the repigmentation of hair.

Palmitoyl Tripeptide-38 also known as Pal-KMO2K is a matrikine-mimetic peptide, that stimulates hyaluronic acid and collagen production.
Phytosonic™ is a complex herbal anti-cellulite ingredient from Sederma designed to combat fatty tissue hypertrophy by acting on pre-adipocytes and mature adipocytes.
This ingredient based on peptide technology and phytochemistry fights the follicle aging process and prevents hair loss.