Pal-KT (Palmitoyl Dipeptide-7) is the shortest matrikine lipo-peptide with anti-aging action that repeats the part of the sequence (palmitoyl-lysine-threonine) of the famous Matrixyl™ pentapeptide (Pal-KTTKS) and exhibits similar properties, boosting extracellular matrix (ECM) components producti
Anti-aging
Many people consider preventing skin aging one of their most essential needs. Over the years, the cosmetic industry has strengthened this wish with new formulations and active ingredients. Consumers highly appreciate good looks and well-being.
Active anti-aging ingredients are participating in both directions. The tests on human volunteers demonstrated the positive influence of many modern ingredients and complexes against skin aging.
The active support of energy control in the cells and the prevention of DNA damage are essential steps to counteract the process of accelerated aging, often induced by UV light. The specific combinations of anti-aging ingredients and complexes do even more.
Strong regenerative effects, like stimulating collagen, support the consumer's need for well-being, resulting in improved skin elasticity and wrinkle reduction. The more consumers learn from the concepts and claims of cosmetic products containing anti-aging ingredients, the higher their expectations are. This section fulfills the increasing requirements of quickly learning consumers.Palmitoyl Dipeptide-10 is a synthetic lipopeptide (Sequence Pal-Ala-His) with Carnosine-like action. It is also known under the trade names SunPEP Di-100 and C-Pep™.
Palmitoyl Hexapeptide-12, also known as Biopeptide El™, is a conjugate of Palmitic acid and a peptide with a sequence Val-Gly-Val-Ala-Pro-Gly, known as a fragment of the protein called elastin.
Palmitoyl Hexapeptide-14 (former Palmitoyl Hexapeptide-6) is a short bioactive peptide with a lipid delivery system for deeper penetration into the skin. It is an anti-aging lipo-peptide that stimulates skin the proliferation of dermal fibroblast cells boosting collagen production.
Palmitoyl Hexapeptide-52 is a synthetic lipopeptide that inhibits acetylcholine release into the synaptic cleft and expression muscle contractions.
Palmitoyl sh-Tripeptide-1 Amide is a low molecular weight synthetic recombinant lipo-peptide derived from FGF-1 (fibroblast growth factor -1) that is involved in various cellular processes, including angiogenesis, keratinocyte organization, and wound healing.
Palmitoyl sh-Tripeptide-3 Amide is a low molecular weight lipo-peptide derived from Epidermal Growth Factor (EGF) that stimulates cell growth, proliferation, and differentiation by binding to its receptor EGFR. It is also known under the trade name Synepin™.
Palmitoyl Tetrapeptide-7 (also known as Rigin™) is a lipopeptide from Sederma designed to mimic DHEA activity and restore cytokine balance to mature skin.
Palmitoyl Tetrapeptide-72 Amide is a synthetic lipo-peptide with sequence Pal-His-Tyr-Arg-Ala-NH2 that boosts expression and production of Mohawk, a homeodomain protein abundantly expressed in the young skin and actively involved in the regeneration of EMC components and connective tis
Palmitoyl Tripeptide-1 stimulates fibroblasts and enhances the production of collagen and GAGs, smoothing fine lines and deep wrinkles and improving the water-binding ability and elasticity of the skin.
Palmitoyl tripeptide-28 is a peptide ingredient based on TGF-β (Transforming growth factor beta) that mimics cytokine action by binding with specific receptors (TGF beta receptor 2) on fibroblast membrane, stimulating the production of extracellular matrix (ECM) components.
Palmitoyl Tripeptide-37 is a synthetic lipo-peptide with sequence Pal-KFK (Palmitoyl-Lys-Phe-Lys) that leaves thrombospondin-like action. It is an analog of Lipospondin. It is an ester of palmitic acid and Tripeptide-37 (KFK peptide) with an active Thrombospondin domain sequence.
Palmitoyl Tripeptide-38 also known as Pal-KMO2K is a matrikine-mimetic peptide, that stimulates hyaluronic acid and collagen production.
Panthenol is a provitamin of Pantothenic acid (vitamin B5), part of the B-complex group, is present in all living cells and is a constituent of coenzyme A. The critical function of this coenzyme is to act as a carrier in acetylation reactions (Krebs cycle).
A symbol of beauty worn by royalty for thousands of years, the pearl is a traditional symbol of luxury and opulence. In Asia, pearl is used for more than ornamentation and decoration; it is a conventional medicine used for cosmetics.
Pelvetia Canaliculata Extract is a seaweed extract in which two cytokinins have been identified (Indole-3 acetic acid and benzylaminopurine). Those cytokinins are vegetable growth hormones.
Pentapeptide-3 is a synthetic peptide with the sequence Gly-Pro-Arg-Pro-Ala-NH2 known under the trade name Vialox peptide. It acts as an acetylcholine (ACh) competitive antagonist, blocking the membrane’s receptors and leaving a curare-like effect.
Coenzyme Q10 is present in dermal cells, where it stimulates ATP (cellular energy molecules) production and protects from oxidative damage (free radicals).
Pentapeptide-4 (former Pentapeptide-3) is a synthetic peptide with the sequence KTTKS (Lys-Thr-Thr-Lys-Ser-OH), a fragment of pro-collagen I. It is known under the trade name Micro-Collagen™. It stimulates the production of dermal matrix components by fibroblasts.
Pentapeptide-48 is a synthetic peptide with the sequence Thr-Arg-Ser-Glu-Leu that repeats the active part of the Royalactin protein. Royalactin is a protein found in royal jelly and it is responsible for the epigenetic changes in the larvae's DNA, creating the queen bee phenotype.
Pentapeptide-59 is a synthetic peptide derived from a part of a sequence (Arg-Arg-Arg-Phe-Val) of
It has been well documented that extracts from yeast fermentation, in particular, Saccharomyces cerevisiae, have demonstrated wound healing properties.
Persea Gratissima Oil Unsaponifiables is the fraction of avocado oil that is not saponified in the refining recovery of avocado oil fatty acids. It contains about 30% of phytosterols, mainly Sitosterol, Campesterol, and Stigmasterol.
Persea Gratissima Sterols are active lipid phytosterols from avocados that lessen the inflammatory effects of UV damage to the skin. This indicates that this natural ingredient may help prevent premature skin aging due to UV radiation.
Matrikines are skin messenger peptides that instruct skin cells to reorganize and re-assemble the extracellular matrix. There are a lot of synthetic matricaines usually in the form of lipo-peptides have been used in cosmetics.
PhytosteCol is a complex of encapsulated phytosterol and vitamin C to improve skin barrier function. Based on phytosterol delivery that provides 80% greater penetration into the skin thanks to lipid vesicles, it is a nutraceutical that nourishes and hydrates mature skin.
Plantago Lanceolata Leaf Extract is a clear orange to brown liquid, a natural ingredient called “The Lance Against Skin Damage,” as it reduces signs of aging due to its antioxidant properties.
Platinum MatrixEM is a synthetic peptide based on TGF (Transforming growth factor) nano-conjugated to platinum particles.
For years, aging induced by sun exposure was called photoaging, attributed only to the UV spectrum of light. However, infrared rays and their heating bring a loss of elasticity and firmness, leading to the appearance of premature wrinkles.
Porphyra Umbilicalis Extract is obtained from red alga and contains isolated mycosporine-like amino acids which are a natural defense component against UVA radiation. The isolated mycosporine-like amino acids absorb maximally at 335 nm with a molar absorption coefficient of 45'000.